Phospho-BID (Ser78) Antibody

• Catalog number
  A1152-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  BID
• Target Alternative Name
  BH3-interacting domain death agonist, p22 BID, BID
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, Mouse
• Immunogen Sequence
  KLH-conjugated synthetic peptide encompassing a sequence within the center region of human BID
• Accession
  P55957
• Gene Id
  637
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
• Purification
  Affinity purified
• Application
  WB, IH
• Positive Control
  WB: mouse spleen, rat spleen lysates; IHC: human brain tissue
• Application And Usages
  WB; 1:500 – 1:2000, IHC; 1:50 – 1:200
• Description
  Bid, a BH3 domain-containing proapoptotic Bcl-2 family member, is localized in the cytosolic fraction of cells as an inactive precursor. Its active form is generated upon proteolytic cleavage by caspase-8 in the Fas signaling pathway. Cleaved Bid translocates to mitochondria and releases its potent proapoptotic activity, which in turn induces cytochrome c release and mitochondrial damage. The cytochrome c releasing activity of Bid was antagonized by Bcl-2. Mutation in the SH3 domain can diminish the cytochrome c releasing activity. In the animal model studies, Bid-deficient mice are found resistant to the lethal effects of death factor signals relayed through Fas.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans
• Handling
  The antibody solution should be gently mixed before use
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Phospho-BID   Ser78  
• Gene symbol
  BID
• Short name
  Phospho-BID (Ser78) Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  phosphorilated-BH3 interacting domain death a this GO nist (Ser78) (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  BH3 interacting domain death a this GO nist, FP497, BID and IDBG-1050 and ENSG00000015475 and 101929618,637, ubiquitin protein ligase binding, Plasma membranes, Bid and IDBG-184076 and ENSMUSG00000004446 and 12122, BID and IDBG-641320 and ENSBTAG00000013988 and 510373,782484

Gene info

• Identity
  HGNC:1050
• Gene
  BID
• Long gene name
  BH3 interacting domain death agonist
• GenBank acession
  • AF042083
• Locus
  22q11.21
• Discovery year
  1998-04-20
• Entrez gene record
  637
• Pubmed identfication
  • 8918887
  • 9721221
• RefSeq identity
  • NM_197966
• Classification
  • MicroRNA protein coding host genes
  • BCL2 homology region 3 (BH3) only
  • Receptor ligands
• VEGA ID
  OTTHUMG00000150087

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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