Eotaxin-2/CCL24, murine recombinant

• Catalog number
  7137-10
• Price
  Please ask
• Size
  10 ug

• Synonyms
  CCL24
• Alternative_names
  CCL24
• Description
  A CC chemokine that signals through the CCR3 receptor
• Recombinant
  Yes
• Source
  E. coli.
• Purity by SDS PAGE
  ≥98%
• Assay
  SDS-PAGE
• Endotoxin Level
  < 0.1 ng/ug of protein (
• Activity Specifications test method
  Determined by its ability to chemoattract murine lymphocytes using a concentration range of 10.0-100.0 ng/ml.
• Biological activity
  Determined by its ability to chemoattract murine lymphocytes using a concentration range of 10.0-100.0 ng/ml.
• Molecular Weight
  10.3 kDa
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized powder
• Physical form description
  Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.
• Reconstitution Instructions
  Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
• Background Information
  Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the murine homolog, without C-terminal truncation). Recombinant murine Eotaxin-2 is a 10.3 kDa protein containing 93 amino acid residues.
• Amino acid sequence
  VTIPSSCCTS FISKKIPENR VVSYQLANGS ICPKAGVIFI TKKGHKICTD PKLLWVQRHI QKLDAKKNQP SKGAKAVRTK FAVQRRRGNS TEV
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Eotaxin-2/CCL24   murine  
• Gene symbol
  CCL24
• Short name
  Eotaxin-2/CCL24, murine recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  Eotaxin-2/chemokine (C-C motif) ligand 24, murine Rec.
• Alternative technique
  rec
• Alternative to gene target
  chemokine (C-C motif) ligand 24, Ckb-6 and MPIF-2 and MPIF2 and SCYA24, CCL24 and IDBG-22726 and ENSG00000106178 and 6369, chemokine activity, Extracellular, Ccl24 and IDBG-203945 and ENSMUSG00000004814 and 56221, BT.32408 and IDBG-640099 and ENSBTAG00000026275 and 617258

Gene info

• Identity
  HGNC:10623
• Gene
  CCL24
• Long gene name
  C-C motif chemokine ligand 24
• Synonyms gene
  • SCYA24
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 24
  • chemokine (C-C motif) ligand 24
• Synonyms
  • Ckb-6
  • MPIF-2
  • eotaxin-2
  • MPIF2
• Synonyms name
  • CK-beta-6
  • myeloid progenitor inhibitory factor 2
  • eotaxin-2
• GenBank acession
  • U85768
• Locus
  7q11.23
• Discovery year
  1997-11-14
• Entrez gene record
  6369
• Pubmed identfication
  • 9104803
  • 9598329
• RefSeq identity
  • NM_002991
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000156635

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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