Eotaxin-2/CCL24, murine recombinant
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Catalog number
7137-10
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Price
Please ask
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Size
10 ug
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Synonyms
CCL24
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Alternative_names
CCL24
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Description
A CC chemokine that signals through the CCR3 receptor
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Recombinant
Yes
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Source
E. coli.
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Purity by SDS PAGE
≥98%
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Assay
SDS-PAGE
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Endotoxin Level
< 0.1 ng/ug of protein (
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Activity Specifications test method
Determined by its ability to chemoattract murine lymphocytes using a concentration range of 10.0-100.0 ng/ml.
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Biological activity
Determined by its ability to chemoattract murine lymphocytes using a concentration range of 10.0-100.0 ng/ml.
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Molecular Weight
10.3 kDa
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Storage Temp
-20°C
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Shipping
Gel Pack
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Shelf Life
12 months
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Appearance
Lyophilized powder
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Physical form description
Sterile filtered through a 0.2 micron filter. Lyophilized with no additives.
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Reconstitution Instructions
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
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Background Information
Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78 amino acid residues (92 a.a. residues for the murine homolog, without C-terminal truncation). Recombinant murine Eotaxin-2 is a 10.3 kDa protein containing 93 amino acid residues.
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Amino acid sequence
VTIPSSCCTS FISKKIPENR VVSYQLANGS ICPKAGVIFI TKKGHKICTD PKLLWVQRHI QKLDAKKNQP SKGAKAVRTK FAVQRRRGNS TEV
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Gene symbol
CCL24
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Short name
Eotaxin-2/CCL24, murine recombinant
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Alternative name
Eotaxin-2/chemokine (C-C motif) ligand 24, murine Rec.
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Alternative technique
rec
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Alternative to gene target
chemokine (C-C motif) ligand 24, Ckb-6 and MPIF-2 and MPIF2 and SCYA24, CCL24 and IDBG-22726 and ENSG00000106178 and 6369, chemokine activity, Extracellular, Ccl24 and IDBG-203945 and ENSMUSG00000004814 and 56221, BT.32408 and IDBG-640099 and ENSBTAG00000026275 and 617258
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Gene info
MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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