CD68, human recombinant

• Catalog number
  7343-50
• Price
  Please ask
• Size
  50 ug

• Synonyms
  Macrosialin, GP110, LAMP4, SCARD1
• Alternative_names
  Macrosialin, GP110, LAMP4, SCARD1
• Description
  A glycoprotein which binds to low density lipoprotein
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥85%
• Assay
  SDS-PAGE
• Molecular Weight
  34.1 kDa (323 aa, 22-319 aa + His Tag), confirmed by MALDI-TOF.
• Storage Temp
  -80°C
• Shipping
  Dry Ice
• Shelf Life
  12 months
• Concentration
  1 mg/ml
• Appearance
  Liquid
• Physical form description
  1 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.1 M NaCl, 1 M Urea and 10% glycerol.
• Background Information
  Macrosialin, also known as CD68, is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. It is found in cytoplasmic granules and in the cytoplasm of various non-hematopoietic tissues including liver and kidney tubules and glomeruli. CD68 is also found, to a lesser extent, on the surface of macrophages, monocytes, neutrophils, basophils and large lymphocytes. Recombinant human CD68 protein, fused to His-tag at N-terminus, was expressed in E.coli.
• Amino acid sequence
  MGSSHPLHHH SSGLVPRGSH MGSHMNDCPH KKSATLLPSF TVTPTVTEST GTTSHRTTKS HKTTTHRTTT TGTTSHGPTT ATHNPTTTSH GNVTVHPTSN STATSQGPST ATHSPATTSH GNATVHPTSN STATSPGFTS SAHPEPPPPS PSPSPTSKET IGDYTWTNGS QPCVHLQAQI QIRVMYTTQG GGEAWGISVL NPNKTKVQGS CEGAHPHLLL SFPYGHLSFG FMQDLQQKVV YLSYMAVEYN VSFPHAAQWT FSAQNASLRD LQAPLGQSFS CSNSSIILSP AVHLDLLSLR LQAAQLPHTG VFGQSFSCPS DRS
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CD68  
• Gene symbol
  CD68
• Short name
  CD68, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  CD68 molecule, H. sapiens Rec.
• Alternative technique
  rec
• Alternative to gene target
  CD68 molecule, GP110 and LAMP4 and SCARD1, CD68 and IDBG-25923 and ENSG00000129226 and 968, Plasma membranes, Cd68 and IDBG-191443 and ENSMUSG00000018774 and 12514, CD68 and IDBG-635034 and ENSBTAG00000000133 and 504960

Gene info

• Identity
  HGNC:1693
• Gene
  CD68
• Long gene name
  CD68 molecule
• Synonyms gene name
  • CD68 antigen
• Synonyms
  • SCARD1
  • macrosialin
  • GP110
  • DKFZp686M18236
  • LAMP4
• Synonyms name
  • scavenger receptor class D, member 1
  • CD68 antigen
  • macrophage antigen CD68
• GenBank acession
  • S57235
• Locus
  17p13.1
• Discovery year
  1993-06-11
• Entrez gene record
  968
• Pubmed identfication
  • 9790779
• RefSeq identity
  • NM_001251
• Classification
  • Scavenger receptors
  • Lysosome associated membrane proteins
  • CD molecules
• VEGA ID
  OTTHUMG00000108146

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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