Low affinity IgE Fc receptor Antibody

• Catalog number
  abx109318
• Price
  Please ask
• Size
  100 μg

• Category
  Primary Antibodies
• Clonality
  Polyclonal
• Raised in
  Rabbit
• Target
  Low affinity IgE Fc receptor
• Immunogen
  see included datasheet or contact us
• Species reactivity
  Human, Mouse, Rat (for other species please inquire)
• Purification
  Affinity purified
• Applications
  WB (for other applications please contact us)
• Stock availability
  Shipped within 5-10 working days.
• Storage conditions
  Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
• Footnote
  This product is for research use only.
• Other products
• Test
  A high affinity purification column was use to purify IgE Fc receptor Antibody by Abbexa by chromatographic size exclusion.
• Properties
  If you buy Antibodies supplied by Abbexa they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Immunoglobulin E (IgE) kappa or Fc specific antibody is a kind of antibody (or immunoglobulin (Ig) "isotype") that has only been found in mammals. IgE is synthesized by plasma cells. Monomers of IgE consist of two heavy chains (ε chain) and two light chains, with the ε chain containing 4 Ig-like constant domains (Cε1-Cε4). IgEs play a role in allergy and response to parasite infection. High levels of IgEs caused by parasites can lower the allergic reaction of patients to allergens common present in the human environment. As such the parasite history of an allergic patient needs to be taken in consideration as a positive factor.
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• French translation
  anticorps

• Gene target
  receptor  
• Gene symbol
  FCRLB, FCRL1, FCGR1A
• Short name
  IgE Fc receptor Antibody
• Technique
  affinity, Antibody, IgE, FC, antibodies against human proteins, antibodies for, IgEs
• Isotype
  IgE, IgE
• Label
  Unconjugated
• Alternative name
  Low protein immunoglobuline E fragment c receptor (antibody to-)
• Alternative technique
  antibodies, immunoglobulin-e

Gene info

• Identity
  HGNC:26431
• Gene
  FCRLB
• Long gene name
  Fc receptor like B
• Synonyms gene
  • FCRLM2
• Synonyms gene name
  • Fc receptor-like and mucin-like 2
  • Fc receptor-like B
• Synonyms
  • FLJ31052
  • FCRL2
  • FREB-2
  • FCRLY
• GenBank acession
  • AY670683
• Locus
  1q23.3
• Discovery year
  2005-05-10
• Entrez gene record
  127943
• Pubmed identfication
  • 15676285
• RefSeq identity
  • NM_152378
• Classification
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000133629

Gene info

• Identity
  HGNC:18509
• Gene
  FCRL1
• Long gene name
  Fc receptor like 1
• Synonyms gene name
  • Fc receptor-like 1
• Synonyms
  • FCRH1
  • IRTA5
  • IFGP1
  • CD307a
• GenBank acession
  • BC033690
• Locus
  1q23.1
• Discovery year
  2005-03-22
• Entrez gene record
  115350
• Pubmed identfication
  • 11493702
  • 11929751
• RefSeq identity
  • NM_052938
• Classification
  • CD molecules
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000019398

Gene info

• Identity
  HGNC:3613
• Gene
  FCGR1A
• Long gene name
  Fc gamma receptor Ia
• Synonyms gene name
  • Fc fragment of IgG, high affinity Ia, receptor for (CD64)
  • Fc fragment of IgG, high affinity Ia, receptor (CD64)
  • Fc fragment of IgG receptor Ia
• Synonyms
  • CD64
  • CD64A
  • FcgammaRI
  • FcgammaRIa
  • FCG1
  • FCGR1
• Synonyms name
  • Fc gamma RI
• GenBank acession
  • BC032634
• Locus
  1q21.2
• Discovery year
  1992-12-03
• Entrez gene record
  2209
• Pubmed identfication
  • 8697799
  • 9763663
• RefSeq identity
  • NM_000566
• Classification
  • CD molecules
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000012089
• Locus Specific Databases
  • FCGR1Abase: Mutation registry for CD64 deficiency
  • LRG_59

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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