Synonym names BACE1 Ser498; BACE1 S498; p-BACE1 Ser498; p-BACE1 Se498; APP beta secretase; Asp 2; ASP2; Aspartyl protease 2; BACE 1; BACE; Beta secretase 1; Beta secretase; Beta site amyloid beta A4 precursor protein cleaving enzyme; Beta site amyloid precursor protein cleaving enzyme 1; Beta site amyloid precursor protein cleaving enzyme; Beta site APP cleaving enzyme 1; Beta site APP cleaving enzyme; FLJ90568; HSPC104; KIAA1149; Memapsin-2; Memapsin 2; Memapsin2; Membrane associated aspartic protease 2; Transmembrane aspartic proteinase Asp2; BACE1_HUMAN; Beta-secretase 1; Beta-site amyloid precursor protein cleaving enzyme 1; Beta-site APP cleaving enzyme 1; Membrane-associated aspartic protease 2.
Clonality Polyclonal antibody
Category Primary Antibodies
Also known as BACE1 (Ser498) PAb
Other size please contact us to order other different size
Source KLH conjugated synthetic phosphopeptide derived from human BACE1 around the phosphorylation site of Ser498
Cross reactivity Human, Mouse, Rat
Specificity This is a highly specific antibody against BACE1 Ser498.
Long name BACE1 (Ser498) Primary Polyclonal Antibody
Products_type ELISA Kit
Gene ID number 23621
Tested Applications WB, IHC-P, IF(IHC-P)
Recommended dilutions WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Modification site(s) Ser498
Background of the target antigen Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein(APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq].
Concentration 1ug per 1ul
Purification method This antibody was purified via Protein A.
Cross reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Target Antigen BACE1 Ser498
Storage conditions Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
Clone number Polyclonal antibody