Jasplakinolide, jaspis johnstoni

  • Catalog number
    1689-05
  • Price
    Please ask
  • Size
    50 ug
  • Description
    A cell- permeable, non-fluorescent F-actin probe. Displays antifungal and antitumor properties. A potent inducer of actin polymerization and stabilization, Jasplakinolide competes with phallotoxins for actin binding (Kd = 15 nM). It also enhances apoptosis induced by IL-2 deprivation.
  • CAS Number
    102396-24-7
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₃₆H₄₅BrN₄O₆
  • Molecular Weight
    709.67
  • Cell Permeable
    Yes
  • Purity
    ≥95% by HPLC
  • Solubilities
    DMSO or MeOH
  • Handling
    Protect from air and light
  • Tag Line
    A non-fluorescent F-actin probe
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24 months
  • MDL Number
    MFCD00873735
  • PubChem CID
    6436289
  • SMILES
    CC1CC(OC(=O)CC(NC(=O)C(N(C(=O)C(NC(=O)C(CC(=C1)C)C)C)C)CC2=C(NC3=CC=CC=C32)Br)C4=CC=C(C=C4)O)C
  • InChi
    InChI=1S/C36H45BrN4O6/c1-20-15-21(2)17-23(4)47-32(43)19-30(25-11-13-26(42)14-12-25)40-35(45)31(18-28-27-9-7-8-10-29(27)39-33(28)37)41(6)36(46)24(5)38-34(44)22(3)16-20/h7-15,21-24,30-31,39,42H,16-19H2,1-6H3,(H,38,44)(H,40,45)/b20-15+/t21-,22+,23-,24-,30+,31+/m0/s1
  • InChi Key
    GQWYWHOHRVVHAP-HZIRKPFGSA-N
  • MSDS Available
    Yes
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