anti-Trail Antibody

• Catalog number
  1113
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  Trail Antibody: Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand in the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel member in the TNF family was recently identified and designated TRAIL (for TNF-related apoptosis-inducing ligand) and Apo-2L (for Apo-2 ligand)1, TRAIL is a type II membrane protein and expressed in a variety of human tissues. Two novel death domain containing receptors DR4 and DR5 have been identified as the receptor for TRAIL3-6. Like TNF and Fas ligand, TRAIL induces apoptosis and NF-kB activation in many tissues and cells.
• Gene names
  Trail Antibody: TL2, APO2L, CD253, TRAIL, Apo-2L, Tumor necrosis factor ligand superfamily member 10, Apo-2 ligand
• Antibodie s label
  unlabelled serum
• Purity
  Trail Antibody is Ion exchange chromatography purified.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Antigen
  TRAIL antibody was made against a peptide corresponding to amino acids near the carboxy terminus of human TRAIL.
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry
• Antibody advice
  TRAIL antibody can be used for detection of TRAIL by Western blot at 1 ug/mL dilution. Antibody can also be used for immunohistochemistry starting at 20 ug/mL.
• Suspention pH azide
  Trail Antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  Trail antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
• Works with
  Human
• Omim nr
  4507593
• Ncbi nr
  NP_003801
• Vial with antibody
  in solution
• NCBI GENE nr
  8743
• GENE symbol
  TNFSF10
• Antigene name
  tumor necrosis factor (ligand) superfamily, member 10
• Source
  Homo sapiens
• Protein nr
  P50591
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Trail  
• Gene symbol
  TNFSF10, TNFRSF10B
• Short name
  anti-Trail Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toTrail (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11925
• Gene
  TNFSF10
• Long gene name
  TNF superfamily member 10
• Synonyms gene name
  • tumor necrosis factor (ligand) superfamily, member 10
• Synonyms
  • TRAIL
  • Apo-2L
  • TL2
  • CD253
• GenBank acession
  • U37518
• Locus
  3q26
• Discovery year
  1998-12-04
• Pubmed identfication
  • 8777713
  • 8663110
• Classification
  • CD molecules
  • Tumor necrosis factor superfamily
• VEGA ID
  OTTHUMG00000156917

Gene info

• Identity
  HGNC:11905
• Gene
  TNFRSF10B
• Long gene name
  TNF receptor superfamily member 10b
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 10b
• Synonyms
  • DR5
  • KILLER
  • TRICK2A
  • TRAIL-R2
  • TRICKB
  • CD262
  • TRAILR2
• GenBank acession
  • AF012628
• Locus
  8p21.3
• Discovery year
  1998-12-04
• Entrez gene record
  8795
• Pubmed identfication
  • 9285725
  • 9311998
• RefSeq identity
  • NM_147187
• Classification
  • Tumor necrosis factor receptor superfamily
  • CD molecules
• VEGA ID
  OTTHUMG00000097826

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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