LAP2 alpha Antibody

• Catalog number
  bs-13709R
• Price
  Please ask
• Size
  0.1ml

• Long name
  LAP2 alpha Primary Polyclonal Antibody
• Also known as
  LAP2 alpha PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  LAP2 alpha
• Specificity
  This is a highly specific antibody against LAP2 alpha.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LAP2
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The nuclear envelope separates the nucleoplasm from the cytoplasm in eukaryotic cells and includes the outer and inner nuclear membrane, nuclear pore complexes and the nuclear lamina. The nuclear lamina contains intermediate filament-type proteins called lamins that form a dense network to strengthen and stabilize the nuclear envelope. Lamina-associated polypeptide 2 (LAP2) is also known as thymopoietin. LAP2 is a nuclear envelope protein and contains an amino-terminal region called the LAP2-emerin-MAN1 or LEM motif. LAP2 also contains a unique DNA-binding amino-terminal domain. Alternative splicing produces six isoforms (α, β,γ, ε and δ) of mammalian LAP2 and three isoforms in Xenopus LAP2. LAP2α and LAP2β associate with chromosomal barrier-to-autointegration factor (BAF) and may play a role in stabilizing chromatin structure. LAP2β also binds to lamin B. LAP2α is a non-membrane isoform of LAP2 that associates with the internal nucleoskeleton and binds lamin A. The gene encoding human LAP2 maps to chromosome 12q23.1.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Isoforms beta/gamma; Lamina associated polypeptide 2 alpha; Lamina associated polypeptide 2; LAP2; Thymopoietin; Thymopoietin isoform alpha; TMPO; TP alpha; TP; LAP2 alpha; LAP2A_HUMAN.
• Description
  The Anti-LAP2 alpha is a α- or alpha protein sometimes glycoprotein present in blood.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  LAP2   alpha  
• Gene symbol
  ERBIN, TMPO
• Short name
  Anti-LAP2 alpha
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  LAP2 alpha Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:15842
• Gene
  ERBIN
• Long gene name
  erbb2 interacting protein
• Synonyms gene
  • ERBB2IP
• Synonyms gene name
  • erbb2-interacting protein
• Synonyms
  • LAP2
• Synonyms name
  • densin-180-like protein
  • ERBB2-interacting protein
• Locus
  5q12.3
• Discovery year
  2001-06-18
• Entrez gene record
  55914
• Pubmed identfication
  • 10574462
  • 10878805
• RefSeq identity
  • NM_018695
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000097808

Gene info

• Identity
  HGNC:11875
• Gene
  TMPO
• Long gene name
  thymopoietin
• Synonyms
  • TP
  • LAP2
  • LEMD4
• Synonyms name
  • LEM domain containing 4
• Locus
  12q23.1
• Discovery year
  1994-11-08
• Entrez gene record
  7112
• Pubmed identfication
  • 7517549
• RefSeq identity
  • NM_003276
• Classification
  • LEM domain containing
• VEGA ID
  OTTHUMG00000170210
• Locus Specific Databases
  • LRG_443

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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