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XL019 for cell activation

XL019 for cell activation is available 2 times from Biovision labs

2609-25 | XL019 for cell activation size: 25 mg | 519.65 USD

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2609-5 | XL019 for cell activation size: 5 mg | 173.59 USD

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Other name (S)-N-(4-(2-((4-morpholinophenyl)amino)pyrimidin-4-yl)phenyl)pyrrolidine-2-carboxamide  
Supplied with N/A
Description XL019 is a potent, highly selective and reversible JAK2 inhibitor (IC₅₀ = 2.2 nM). Inhibits JAK1 (IC₅₀ = 134.3 nM), JAK3 (IC50 = 214.2 nM) and TYK2 (IC₅₀ = 348.3 nM) at higher concentrations. XL019 displays significant dose-dependent pharmacodynamic and antitumor effect in a mouse xenograft model.
Category Biochemicals
Molecular formula C₂₅H₂₈N₆O₂
Is it cell-permeable? Yes
Molecular weight 444.53
Storage condition -20 ̊C
Shipping condition Gel pack
Purification >98% by HPLC
Peptide sequence N/A
Is this a salt? No
CAS number 945755-56-6
Storage instructions Protect from air and light
Maximum time for storage 36 months
Physical appearance Light yellow to light brown solid
Reconstitute instructions DMSO (~ 15 mg/ml)
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetXL019 for activation
Short name XL019 for activation
Technique activation
Alternative name XL019 to measure cellular activation
Tissue cell
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