Ro3280

  • Catalog number
    B1175-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    4-((9-cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino)-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide
  • Description
    RO3280 is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1 (IC₅₀ = 3 nM).
  • CAS Number
    1062243-51-9
  • Structure Available
    Yes
  • Molecular Formula
    C₂₇H₃₅F₂N₇O₃
  • Molecular Weight
    543.61
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A potent, highly selective inhibitor of Polo-like kinase 1
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    25015677
  • SMILES
    CN1CCC(CC1)NC(=O)C2=CC(=C(C=C2)NC3=NC=C4C(=N3)N(CC(C(=O)N4C)(F)F)C5CCCC5)OC
  • InChi
    InChI=1S/C27H35F2N7O3/c1-34-12-10-18(11-13-34)31-24(37)17-8-9-20(22(14-17)39-3)32-26-30-15-21-23(33-26)36(19-6-4-5-7-19)16-27(28,29)25(38)35(21)2/h8-9,14-15,18-19H,4-7,10-13,16H2,1-3H3,(H,31,37)(H,30,32,33)
  • InChi Key
    DJNZZLZKAXGMMC-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
    Ro3280  
  • Short name
    Ro3280
  • Alternative name
    Ro3280
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