Syndecan 3/SDC3 Antibody

• Catalog number
  PA2133
• Price
  Please ask
• Size
  0,1 mg

• Target antigen
  Syndecan 3/SDC3
• Clonality
  Polyclonal antibody
• Clone
  Polyclonal antibody
• Raised in
  rabbit
• Type of the antibody
  IgG polyclonal antibody
• Product form
  freeze-dried
• Reacts with species
  human
• Analyses
  WB,IHC-P
• Immunogen
  A synthetic peptide corresponding to a sequence at the N-terminus of mouse Syndecan 3/SDC3 (45-60aa AQRWRNENFERPVDLE), identical to the related rat sequence, and different from the related human sequence by one amino acid.
• Product configuration
  Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
• Purification
  Immunogen affinity purified.
• Solubilization
  The powdered antibody should be dissolved in 0.2 ml of distilled water to achieve final concentration of 500ug/ml
• Storage condtions
  Keep the Syndecan 3/SDC3 Antibodyat minus twenty degrees Celsius for 1 year. The ready-to-use solutions can be stored at four degrees Celsius for a month. Our specialsits recommend to freeze the aliquotes at minus twenty degrees Celsius for long-term application. Multiple procedures of freezing and thawing influence the specifity and reactivity of the antibody in a negative way.
• Tips
  The Syndecan 3/SDC3 Antibody did not cross-reacted with other proteins during the test procedures. This antobdy is intended to be used for research analyses and it is not applicale for in vitro diagnostics.
• Background
  Syndecan-3, also called SYND3 is a protein that in humans is encoded by the SDC3 gene. This gene was assigned to human chromosome 1p35.2. This gene can function as in trans HIV receptors via binding of HIV-1 gp120 to the syndecan heparin sulfate chains. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, and possibly by transferring signals from the cell surface in a sugar-dependent mechanism. In wildtype mice, SDC3 was expressed in hypothalamic regions that control energy balance. It was proposed that oscillation of hypothalamic SDC3 levels physiologically modulates feeding behavior.
• Related articles
  1. Berndt, C., Casaroli-Marano, R. P., Vilaro, S., Reina, M. Cloning and characterization of human syndecan-3. J. Cell. Biol. 82: 246-259, 2001. 2. Bobardt, M. D., Saphire, A. C. S., Hung, H.-C., Yu, X., Van der Schueren, B., Zhang, Z., David, G., Gallay, P. A. Syndecan captures, protects, and transmits HIV to T lymphocytes. Immunity 18: 27-39, 2003. 3. de Witte, L., Bobardt, M., Chatterji, U., Degeest, G., David, G., Geijtenbeek, T. B. H., Gallay, P. Syndecan-3 is a dendritic cell-specific attachment receptor for HIV-1.Proc. Nat. Acad. Sci. 104: 19464-19469, 2007. 4. Ha, E., Kim, M.-J., Choi, B.-K., Rho, J.-J., Oh, D.-J., Rho, T.-H., Kim, K.-H., Lee, H. J., Shin, D.-H., Yim, S. V., Baik, H. H., Chung, J.-H., Kim, J. W. Positive association of obesity with single nucleotide polymorphisms of syndecan 3 in the Korean population. J. Clin. Endocr. Metab. 91: 5095-5099, 2006.
• Gene Name
  SDC3
• Protein Name
  Syndecan-3
• Gene Full Name
  syndecan 3
• Synonyms
  N-syndecan antibody|Sdc3 antibody|SDC3_HUMAN antibody|SDCN antibody|SYND3 antibody|syndecan proteoglycan 3 antibody|Syndecan-3 antibody
• Uniprot ID
  Q64519
• Properties
  If you buy Antibodies supplied by boster they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Syndecan   3/SDC3  
• Gene symbol
  SDC3
• Short name
  Syndecan 3/SDC3 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Alternative name
  Syndecan 3/syndecan 3 (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  syndecan 3, SDCN and SYND3, SDC3 and IDBG-95385 and ENSG00000162512 and 9672, cytoskeletal protein binding, Plasma membranes, Sdc3 and IDBG-192888 and ENSMUSG00000025743 and 20970, BT.105251 and IDBG-644791 and ENSBTAG00000026676 and 618198

Gene info

• Identity
  HGNC:10660
• Gene
  SDC3
• Long gene name
  syndecan 3
• Synonyms gene name
  • syndecan 3 (N-syndecan)
• Synonyms
  • N-syndecan
  • SYND3
• Synonyms name
  • syndecan proteoglycan 3
• GenBank acession
  • AF248634
• Locus
  1p35.2
• Discovery year
  1994-05-16
• Entrez gene record
  9672
• Pubmed identfication
  • 1556152
  • 11527150
• RefSeq identity
  • NM_014654
• Classification
  • Syndecans
• VEGA ID
  OTTHUMG00000043646

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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