U-74389G, Lipid peroxidation blocker

• Catalog number
  SIH-205-100MG
• Price
  Please ask
• Size
  100 mg

• Stock availabilitIn Stock
  In Stock
• CAS number
  153190-29-5
• Description
  Lipid peroxidation blocker
• Molecular weight
  726,9 g/mol
• Primary research fields
  Cancer, Apoptosis
• Other name
  21-{4-[2,6-Di(1-pyrrolidinyl)-4-pyrimidinyl]-1-piperazinyl}pregna-1,4,9(11)-triene-3,20-dione (2Z)-2-butenedioate (1:1)
• Product category
  Small Molecules
• Product type
  Inhibitor
• Chemical formula
  C37H50N6O2•C4H4O4
• Origin
  Synthetic
• Purity pourcentage
  >99%
• Soluble in
  Soluble in 25 mg/ml DMSO, and in 20 mg/ml in ethanol; Insoluble in water
• Physical appearance
  White Solid
• Storage recommendations
  -20ºC
• Shipping recommendations
  Shipped Ambient
• Safety information
  Classification: Harmful. May be harmful if inhaled, swallowed or absorbed through skin. Safety Phrases: S22 - Do not breathe dust S24/25 - Avoid contact with skin and eyes S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection
• PubChem number
  104933
• Scientific context
  U-74389G is an antioxidant which prevents iron-dependent lipid peroxidation. It prevents organ damage in intestinal cold storage, preservation and reperfusion injury (1-4).
• Bibliography
  1. Ishizaki N., et al. (1997) Transplantation. 63: 202-208. 2. Perna A.M., et al. (1996) Pharmacol Res. 34: 25-31. 3. Palma-Vargas J.M., et al. (1996) J Surg Res. 66: 131-137. 4. Shoskes D.A., Xie Y., Gonzalez-Cadavid N.F. Transplantation. 63: 495-500.
• Release date
  8-Apr-2011
• PubMed number
  Refer to PubMed
• Tested applications
  To be tested
• Tested reactivity
  To be tested
• Representative figure link
• Representative figure legend
  Chemical structure of U-74389G (SIH-205), a Free radical scavenger. CAS #: 153190-29-5. Molecular Formula: C37H50N6O2 · C4H4O4 . Molecular Weight: 726.9 g/mol. Chemical structure of U-74389G, a Free radical scavenger (SIH-205). CAS # 153190-29-5. Molecular Formula: C37H50N6O2 · C4H4O4 .
• Warning information
  Non-hazardous
• Country of production
  Canada
• Total weight kg
  0.25
• Net weight g
  0.1
• Other related products

• Gene target
  U-74389G   Lipid   peroxidation   blocker  
• Gene symbol
  HLA-U, UTS2, CENPU
• Short name
  U-74389G, Lipid peroxidation blocker
• Alternative name
  U-74389G, Lipid peroxidation blocker

Gene info

• Identity
  HGNC:23477
• Gene
  HLA-U
• Long gene name
  major histocompatibility complex, class I, U (pseudogene)
• Synonyms gene
  • HLA-21
• Synonyms gene name
  • HLA-21 pseudogene
• Synonyms
  • Em:AB023056.13
• GenBank acession
  • M96330
• Locus
  6p22.1
• Discovery year
  2004-01-16
• Entrez gene record
  352965
• RefSeq identity
  • NG_002398
• Classification
  • Histocompatibility complex
• VEGA ID
  OTTHUMG00000031245
• Locus Specific Databases
  • IMGT/HLA Database

Gene info

• Identity
  HGNC:12636
• Gene
  UTS2
• Long gene name
  urotensin 2
• Synonyms
  • UII
  • U-II
  • UCN2
  • PRO1068
• Synonyms name
  • prepro U-II
• GenBank acession
  • AF104118
• Locus
  1p36.23
• Discovery year
  2000-03-22
• Entrez gene record
  10911
• Pubmed identfication
  • 9861051
  • 10499587
• RefSeq identity
  • NM_006786
• Classification
  • Receptor ligands
  • Neuropeptides
• VEGA ID
  OTTHUMG00000001218

Gene info

• Identity
  HGNC:21348
• Gene
  CENPU
• Long gene name
  centromere protein U
• Synonyms gene
  • MLF1IP
• Synonyms gene name
  • MLF1 interacting protein
• Synonyms
  • CENP-U
  • KLIP1
  • CENP-50
  • PBIP1
• Synonyms name
  • polo-box-interacting protein 1
• GenBank acession
  • AK027121
  • AF516710
• Locus
  4q35.1
• Discovery year
  2003-07-17
• Entrez gene record
  79682
• Pubmed identfication
  • 15116101
  • 16622420
  • 16622419
• RefSeq identity
  • NM_024629
• Classification
  • Constitutive centromere associated network
• VEGA ID
  OTTHUMG00000160499

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