LDHAL6B Antibody (NT)

  • Catalog number
    6737-100
  • Price
    Please ask
  • Size
    100 μl
  • Antibody Target
    LDHAL6B
  • Target Alternative Name
    LDHAL6B; LDHAL6; LDHL; L-lactate dehydrogenase A-like 6B
  • Antibody Type
    Polyclonal
  • Species Reactivities
    Human.
  • Immunogen Sequence
    This LDHAL6B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 45-71 amino acids from the N-terminal region of human LDHAL6B.
  • Accession
    Q9BYZ2
  • Gene Id
    92483
  • Appearance
    Colorless liquid
  • Form
    Liquid
  • Formulation
    100 µl of antibody in PBS with 0.09% (W/V) sodium azide
  • Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
  • Application
    Western blot.
  • Positive Control
    Western blot: K562 cell line lysates
  • Application And Usages
    Western blot: ~1:1000.
  • Description
    L-Lactate dehydrogenase A chain (LDHA) is a member of the LDH/MDH superfamily and LDH family. It catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA is localized primarily in muscle tissue and is part of the lactate dehydrogenase family. Mutations in LDHA have been linked to exertional myoglobinuria. LDH1 is decreased in essential thrombocythemia. LDHA is induced through a non-genomic pathway of estrogen action. Reduction in LDH-A activity results in stimulation of mitochondrial respiration and decrease of mitochondrial membrane potential. Mutations in LDHA have been associated with in LDHA are the cause of glycogen storage disease type 11 (GSD11) which is a metabolic disorder that results in exertional myoglobinuria, pain, cramps and easy fatigue.
  • Storage Condition
    -20 °C
  • Shipping Condition
    gel pack
  • Shelf Life
    12 months
  • Usage
    For Research Use Only! Not to be used in humans.
  • Handling
    The antibody solution should be gently mixed before use.
  • Western Blot Verified
    Verified
  • Immunocytochemistry Verified
    Not Verified
  • Immunofluorescence Verified
    Not Verified
  • Immunoprecipitation Verified
    Not Verified
  • ELISA Verified
    Not Verified
  • ChIP Verified
    Not Verified
  • Flow Cytometry Verified
    Not Verified
  • Properties
    If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
    LDHAL6B  
  • Gene symbol
    LDHAL6B
  • Short name
    LDHAL6B Antibody (NT)
  • Technique
    Antibody, antibodies against human proteins, antibodies for
  • Isotype
    Rabbit IgG
  • Alternative name
    LDHAL6B (antibody to-) (NT)
  • Alternative technique
    antibodies
Gene info
MeSH Data
  • Name
  • Concept
    Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
  • Tree numbers
    • E05.196.401.143
    • E05.301.300.096
    • E05.478.566.320.200
    • E05.601.262
    • E05.601.470.320.200
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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