SIRT3 Antibody

• Catalog number
  3223-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  Sirtuin-3
• Target Alternative Name
  NAD-dependent deacetylase sirtuin-3, mitochondrial, SIR2-like protein 3
• Antibody Type
  Polyclonal
• Species Reactivities
  Human
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 387 of human SIRT3
• Accession
  Q9NTG7
• Gene Id
  23410
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  100 µg (0.5 mg/ml) affinity purified rabbit anti- SIRT3 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.01% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot
• Positive Control
  Jurkat cell lysate
• Application And Usages
  Western Blot analysis (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. Blocking peptide (Cat.# 3223BP-50) is available separately.
• Description
  Silent information regulator (Sir2)-like family deacetylases (also known as sirtuins) are highly conserved proteins and have important roles in the regulation of metabolism, inflammation, cellular survival growth and differentiation. SIRT3 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Yeast sirtuin proteins are found to regulate epigenetic gene silencing. Sirtuins are NAD-dependent protein ADP-ribosyl transferase which catalyzes the transfer of ADP-ribosyl groups onto target proteins.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  SIRT3  
• Gene symbol
  SIRT3
• Short name
  SIRT3 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  SIRT3 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:14931
• Gene
  SIRT3
• Long gene name
  sirtuin 3
• Synonyms gene name
  • sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 3
  • sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae)
• Synonyms
  • SIR2L3
• GenBank acession
  • AF083108
• Locus
  11p15.5
• Discovery year
  2001-03-20
• Entrez gene record
  23410
• Pubmed identfication
  • 10381378
  • 18215119
• Classification
  • Sirtuins
• VEGA ID
  OTTHUMG00000119074

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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