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anti-DNMT3a Antibody

anti-DNMT3a Antibody is available 1 time from Biovision labs

3227-100 | anti-DNMT3a Antibody size: DNMT3a Antibody | 413.77 USD

Catalog number 3227-100
Supplier Biovision
Price 413.77 USD
Size DNMT3a Antibody
1. Gene info
Identity 50653
Gene LINC01381
Long gene name long intergenic non-protein coding RNA 1381
Synonyms
  • TCONS_00002860
  • DADOT
Synonyms name
  • DNMT3A antisense downstream transcript
GenBank acession
  • AW515644
Locus 2p23.3
Discovery year 2014-06-04
Entrez gene record 106144568
Classification
  • Long intergenic non-protein coding RNAs
Havana BLAST/BLAT OTTHUMG00000152010
Product images
    #0#.jpegDNMT3a Antibody
Target of this antibody: DNMT3a
Alternative names of antibody target: DNA Methyltransferase 3a, DNMT3A
Background information: Methylation of DNA at cytosine residues plays an important role in regulation of gene expression, genomic imprinting, and is essential for mammalian development. Hypermethylation of CpG islands in tumor suppressor genes or hypomethylation of bulk genomic DNA may be linked with development of cancer. To date, three families of mammalian DNA methyltransferase genes have been identified which include DNMT1, DNMT2, and DNMT3. DNMT1 is constitutively expressed in proliferating cells and inactivation of this gene causes global demethylation of genomic DNA and embryonic lethality. DNMT2 is expressed at low levels in adult tissues and its inactivation does not affect DNA methylation or maintenance of methylation. The DNMT3 family members, DNMT3a and DNMT3b, are strongly expressed in embryonic stem (ES) cells but their expression is down regulated in differentiating ES cells and is low in adult somatic tissue. Recently, it has been shown that naturally occurring mutations of DNMT3b gene occur in patients with a rare autosomal recessive disorder, termed ICF (immunodeficiency, centromeric instability, and facial anomalies) syndrome.
Antibody host: Rabbit
Clonality of antibody: Polyclonal
Isotype: Rabbit Ig
This antibody reacts with: Human, mouse, rat
Immunogene sequence: Synthetic peptide at near N-terminal
Concentration of antibody: 0.5 mg/ml
Form of antibody: Liquid
Formulation of this antibody: 100 µg (0.5 mg/ml) of antibody in PBS, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol, pH 7.2
Purification method: Affinity purified
This antibody has been succesfully tested for use in following methods: Western blot
Recommended usage: Western blot: 1:200
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
How to handle this antibody: The antibody solution should be gently mixed before use.
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetDNMT3a
Short name anti-DNMT3a Antibody
Technique Antibody, anti
Alternative name antibody to-DNMT3a (Antibody to)
Alternative technique antibodies
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anti-DNMT3a Antibody | Technique alternative | 01012192028
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