Bax

• Catalog number
  GEN438413
• Price
  Please ask
• Size
  100ug

• Also known as
  Bax
• Other names
  apoptosis regulator BAX isoform 1; Apoptosis regulator BAX; apoptosis regulator BAX; bcl2-L-4; Baxdelta2G9; Baxdelta2omega; Baxdelta2G9omega; bcl-2-like protein 4; BCL2-associated X protein omega; BCL2-associated X protein; Bcl-2-like protein 4; Bcl2-L-4
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  BAX
• Gene name synonims
  N/A
• Other gene names
  BAX; BAX; BCL2L4; BCL2L4; Bcl2-L-4
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1
• Clone
  2D2
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens), Monkey. Does not react with Mouse (Mus musculus) and Rat (Rattus norvegicus).; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes a protein of 21kDa, identified as the Bax protein. This MAb is highly specific to Bax and shows no cross-reaction with Bcl-2? or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  N/A
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4C. Temperature variations in the range of 1 to 7 degrees Celsius are tolerable. We recommend NOT to freeze the antibody. Antibody is stable for 24 months.
• Tested applications
  ELISA (EIA), Flow Cytometry (FC/FACS), Immunofluorescence (IF), Western Blot (WB), Immunoprecipitation (IP), Immunohistology (IH)

• Gene target
  Bax  
• Gene symbol
  TMBIM7P, TMBIM6, TMBIM1
• Short name
  Bax
• Alternative name
  Anti-Bax
• Alternative to gene target
  BCL2-associated X protein, BCL2L4, BAX and IDBG-61459 and ENSG00000087088 and 581, BH3 domain binding, nuclei, Bax and IDBG-183241 and ENSMUSG00000003873 and 12028, BAX and IDBG-640344 and ENSBTAG00000013340 and 100850136,280730

Gene info

• Identity
  HGNC:49212
• Gene
  TMBIM7P
• Long gene name
  transmembrane BAX inhibitor motif containing 7, pseudogene
• Locus
  7q21.2
• Discovery year
  2013-10-09
• Entrez gene record
  105375396
• Classification
  • Transmembrane BAX inhibitor motif containing
• VEGA ID
  OTTHUMG00000155903

Gene info

• Identity
  HGNC:11723
• Gene
  TMBIM6
• Long gene name
  transmembrane BAX inhibitor motif containing 6
• Synonyms gene
  • TEGT
• Synonyms gene name
  • testis enhanced gene transcript
• Synonyms
  • BI-1
  • BAXI1
• Synonyms name
  • BAX inhibitor 1
• GenBank acession
  • X75861
• Locus
  12q13.12
• Discovery year
  1994-08-30
• Entrez gene record
  7009
• Pubmed identfication
  • 8530040
  • 9660918
• RefSeq identity
  • NM_003217
• Classification
  • Transmembrane BAX inhibitor motif containing
• VEGA ID
  OTTHUMG00000169652

Gene info

• Identity
  HGNC:23410
• Gene
  TMBIM1
• Long gene name
  transmembrane BAX inhibitor motif containing 1
• Synonyms
  • PP1201
  • RECS1
  • LFG3
• GenBank acession
  • BN000408
• Locus
  2q35
• Discovery year
  2005-08-22
• Entrez gene record
  64114
• Pubmed identfication
  • 28481357
• RefSeq identity
  • NM_022152
• Classification
  • Transmembrane BAX inhibitor motif containing
• VEGA ID
  OTTHUMG00000133105

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