NLRP6/NALP6 (NACHT-, LRR and PYD Domains-containing Protein 6, Nod-like Receptor Pyrin Domain-containing Protein 6, NLRP6, Angiotensin II/Vasopressin Receptor, PYRIN-containing APAF1-like Protein 5, NALP6)[NLRP6/NALP6]

• Catalog number
  MBS648927
• Price
  Please ask
• Size
  NA

• Products_type
  Antibody
• Description
  The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.

• Gene target
  NLRP6/NALP6   NACHT   LRR   PYD   Domains   Protein   Nod-like   Receptor   Pyrin   Domain   Protein   NLRP6   Angiotensin   II/Vasopressin   Receptor   PYRIN   APAF1-like   Protein   NALP6   [NLRP6/NALP6]  
• Gene symbol
  NLRP6, APAF1, LRR1, NLRP14
• Short name
  NLRP6/NALP6 (NACHT-, LRR PYD Domains- Protein 6, Nod-like Receptor Pyrin Domain- Protein 6, NLRP6, Angiotensin II/Vasopressin Receptor, PYRIN- APAF1-like Protein 5, NALP6)[NLRP6/NALP6]
• Host
  Mouse
• Alternative name
  NLRP6/NALP6 (NACHT-, LRR and PYD Domains-containing Protein 6, Nod-like Receptor Pyrin Domain-containing Protein 6, NLRP6, Angiotensin II/Vasopressin Receptor, PYRIN-containing apoptotic peptidase activating factor 1-like Protein 5, NALP6)[NLRP6/NALP6]
• Alternative to gene target
  apoptotic peptidase activating factor 1, APAF-1 and CED4, APAF1 and IDBG-52364 and ENSG00000120868 and 317, ADP binding, nuclei, Apaf1 and IDBG-185032 and ENSMUSG00000019979 and 11783, APAF1 and IDBG-636787 and ENSBTAG00000021661 and 537782

Gene info

• Identity
  HGNC:22944
• Gene
  NLRP6
• Long gene name
  NLR family pyrin domain containing 6
• Synonyms gene
  • NALP6
• Synonyms gene name
  • NACHT, leucine rich repeat and PYD containing 6
• Synonyms
  • PYPAF5
  • PAN3
  • CLR11.4
• Synonyms name
  • nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 6
• GenBank acession
  • AF479748
• Locus
  11p15.5
• Discovery year
  2003-10-28
• Entrez gene record
  171389
• Pubmed identfication
  • 12563287
  • 12019269
• RefSeq identity
  • NM_138329
• Classification
  • Pyrin domain containing
  • NLR family
• VEGA ID
  OTTHUMG00000119070

Gene info

• Identity
  HGNC:576
• Gene
  APAF1
• Long gene name
  apoptotic peptidase activating factor 1
• Synonyms gene name
  • apoptotic protease activating factor
  • apoptotic peptidase activating factor
• Synonyms
  • CED4
  • APAF-1
• GenBank acession
  • AF013263
• Locus
  12q23.1
• Discovery year
  1998-01-20
• Entrez gene record
  317
• Pubmed identfication
  • 9267021
  • 10702682
• RefSeq identity
  • NM_181861.1
• Classification
  • Apoptosome
  • WD repeat domain containing
  • Caspase recruitment domain containing
• VEGA ID
  OTTHUMG00000170214

Gene info

• Identity
  HGNC:19742
• Gene
  LRR1
• Long gene name
  leucine rich repeat protein 1
• Synonyms gene
  • PPIL5
• Synonyms gene name
  • peptidylprolyl isomerase (cyclophilin)-like 5
• Synonyms
  • MGC20689
  • LRR-1
• Synonyms name
  • LRR-repeat protein 1
• GenBank acession
  • BC030142
• Locus
  14q21.3
• Discovery year
  2002-11-20
• Entrez gene record
  122769
• Pubmed identfication
  • 11804328
  • 21074724
• RefSeq identity
  • NM_203467
• Classification
  • Cyclophilin peptidylprolyl isomerases
• VEGA ID
  OTTHUMG00000140273

Gene info

• Identity
  HGNC:22939
• Gene
  NLRP14
• Long gene name
  NLR family pyrin domain containing 14
• Synonyms gene
  • NALP14
• Synonyms gene name
  • NACHT, leucine rich repeat and PYD containing 14
• Synonyms
  • NOD5
  • GC-LRR
  • Nalp-iota
  • PAN8
  • CLR11.2
• Synonyms name
  • nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 14
• GenBank acession
  • BK001107
• Locus
  11p15.4
• Discovery year
  2003-10-28
• Entrez gene record
  338323
• Pubmed identfication
  • 12563287
• RefSeq identity
  • NM_176822
• Classification
  • NLR family
  • Pyrin domain containing
• VEGA ID
  OTTHUMG00000165508

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