MOUSE Anti-BCL-2alpha (CLONE SPM117) Antibody

• Catalog number
  GEN462227
• Price
  Please ask
• Size
  100ug

• Also known as
  BCL-2
• Other names
  bcl-2; N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  BCL-2
• Gene name synonims
  N/A
• Other gene names
  N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  N/A
• Clone
  SPM117
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Expression of Bcl-2alpha oncoprotein inhibits the programmed cell death (apoptosis). In most follicular lymphomas, neoplastic germinal centers express high levels of Bcl-2alpha protein, whereas the normal or hyperplastic germinal centers are negative. This antibody recognizes human BCL-2alpha, the other species are not tested.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Synthetic peptide corresponding to aa 41-54 of human Bcl-2alpha.
• Form Appearance
  This affinity purified antibody is supplied in sterile Phosphate-buffered saline (pH7.2) containing antibody stabilizer.
• Concentration
  Size: 100 ug/200 ul
• Storage and shipping
  The antibodies are stable for 12 months from date of receipt when stored the antibody should be stored at -20 degrees Celsius. to -70 degree C. Upon initial thawing, apportion into working aliquots and store at -70 degree C for up to six months. The antibodies can be stored at 2 degree C-8 degree C for one month without detectable loss of activity. Avoid repeated freezing-thawing cycles.
• Tested applications
  Immunohistochemistry - Paraffin, Western Blot, Immunoprecipitation
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  BCL-2alpha   SPM117  
• Gene symbol
  BCL2L1, BCL2L13, BCL2L10, BCL2L14, BCL2, BCL2L2
• Short name
  MOUSE Anti-BCL-2alpha (CLONE SPM117) Antibody
• Technique
  Antibody, anti-, Mouse, anti, antibody to, antibodies, antibodies against human proteins, antibodies for, mouses
• Host
  mouse
• Species
  Mouse, Mouses
• Alternative name
  Anti-MOUSE anti BCL-2alpha (CLONE SPM117)
• Alternative technique
  antibodies, murine
• Clone name
  SPM117

Gene info

• Identity
  HGNC:992
• Gene
  BCL2L1
• Long gene name
  BCL2 like 1
• Synonyms
  • BCLX
  • BCL2L
  • Bcl-X
  • bcl-xL
  • bcl-xS
  • PPP1R52
• Synonyms name
  • protein phosphatase 1, regulatory subunit 52
• GenBank acession
  • Z23115
• Locus
  20q11.21
• Discovery year
  1997-10-30
• Entrez gene record
  598
• Pubmed identfication
  • 8358789
• RefSeq identity
  • NM_138578
• Classification
  • BCL2 family
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000032192

Gene info

• Identity
  HGNC:17164
• Gene
  BCL2L13
• Long gene name
  BCL2 like 13
• Synonyms gene name
  • BCL2-like 13 (apoptosis facilitator)
• Synonyms
  • MIL1
  • BCL-RAMBO
• GenBank acession
  • AF146568
• Locus
  22q11.21
• Discovery year
  2002-09-20
• Entrez gene record
  23786
• Pubmed identfication
  • 11262395
  • 11381032
  • 26146385
• RefSeq identity
  • NM_015367
• Classification
  • BCL2 family
• VEGA ID
  OTTHUMG00000150088

Gene info

• Identity
  HGNC:993
• Gene
  BCL2L10
• Long gene name
  BCL2 like 10
• Synonyms gene name
  • BCL2-like 10 (apoptosis facilitator)
• Synonyms
  • Diva
  • Boo
  • BCL-B
• GenBank acession
  • AF285092
• Locus
  15q21.2
• Discovery year
  1999-05-21
• Entrez gene record
  10017
• Pubmed identfication
  • 9829980
  • 9878060
• Classification
  • BCL2 family
• VEGA ID
  OTTHUMG00000131893

Gene info

• Identity
  HGNC:16657
• Gene
  BCL2L14
• Long gene name
  BCL2 like 14
• Synonyms gene name
  • BCL2-like 14 (apoptosis facilitator)
• Synonyms
  • BCLG
  • BCL-G
• GenBank acession
  • AF281254
• Locus
  12p13.2
• Discovery year
  2004-02-09
• Entrez gene record
  79370
• Pubmed identfication
  • 11054413
• RefSeq identity
  • NM_030766
• Classification
  • BCL2 family
• VEGA ID
  OTTHUMG00000159528

Gene info

• Identity
  HGNC:990
• Gene
  BCL2
• Long gene name
  BCL2 apoptosis regulator
• Synonyms gene name
  • B-cell CLL/lymphoma 2
  • BCL2, apoptosis regulator
• Synonyms
  • Bcl-2
  • PPP1R50
• Synonyms name
  • protein phosphatase 1, regulatory subunit 50
• GenBank acession
  • M14745
• Locus
  18q21.33
• Discovery year
  2001-06-22
• Entrez gene record
  596
• RefSeq identity
  • NM_000633
  • NM_000657
• Classification
  • BCL2 family
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000132791
• Locus Specific Databases
  • LRG_1113

Gene info

• Identity
  HGNC:995
• Gene
  BCL2L2
• Long gene name
  BCL2 like 2
• Synonyms
  • KIAA0271
  • BCL-W
  • PPP1R51
• Synonyms name
  • protein phosphatase 1, regulatory subunit 51
• GenBank acession
  • D87461
• Locus
  14q11.2
• Discovery year
  1997-07-22
• Entrez gene record
  599
• Pubmed identfication
  • 8761287
• RefSeq identity
  • NM_004050
• Classification
  • BCL2 family
  • Protein phosphatase 1 regulatory subunits
• VEGA ID
  OTTHUMG00000028738

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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