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Anti-Mitofusin 2 (Polyclonal), ALEXA Fluor 594

Anti-Mitofusin 2 (Polyclonal), ALEXA Fluor 594 is available 1 time from Bioss polyclonal antibodies labs

GENTObs-2988R-A594 | Anti-Mitofusin 2 (Polyclonal), ALEXA Fluor 594 size: 100 microliters | 569.93 USD

Catalog number GENTObs-2988R-A594
Price 569.93 USD
Size 100 microliters
1. Gene info
Identity 16877
Gene MFN2
Long gene name mitofusin 2
Synonyms
  • CPRP1
  • KIAA0214
  • MARF
  • CMT2A2
GenBank acession
  • AF036536
Locus 1p36.22
Discovery year 2003-02-25
Entrez gene record 9927
Pubmed identfication
  • 12499352
  • 11181170
RefSeq identity
  • NM_014874
Havana BLAST/BLAT OTTHUMG00000002392
Locus Specific Databases
  • Inherited Peripheral Neuropathies Mutation Database
  • LRG_255
Product images
    Formalin-fixed and paraffin embedded human kidney labeled with  Rabbit Anti Mitofusin 2/MFN2 Polyclonal Antibody, Unconjugated (bs-2988R) at 1:200 followed by conjugation to the secondary antibody and DAB stainingFormalin-fixed and paraffin embedded mouse kidney labeled with  Rabbit Anti Mitofusin 2/MFN2 Polyclonal Antibody, Unconjugated (bs-2988R) at 1:200 followed by conjugation to the secondary antibody and DAB stainingFormalin-fixed and paraffin embedded human kidney labeled with Rabbit Anti-Mitofusin 2 Polyclonal Antibody, Unconjugated (bs-2988R) at 1:200 followed by Goat Anti-Rabbit IgG, FITC conjugated(bs-0295G-FITC)used at 1:200 dilution for 40 minutes at 37°CFormalin-fixed and paraffin embedded human breast cancer tissue labeled with Anti-Mitofusin 2 Polyclonal Antibody, Unconjugated (bs-2988R) at 1:200 followed by conjugation to the secondary antibody and DAB staining.
Type Conjugated Primary Antibody
Conjugated with ALEXA FLUOR® 594
Host organism Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide Mitofusin 2
Specificity This antibody reacts specifically with Mitofusin 2
Modification No modification has been applied to this antibody
Modification site None
Clonality Polyclonal Antibody
Clone Polyclonal Antibodies
Concentration 1ug per 1ul
Subcellular locations Cytoplasm
Antigen Source KLH conjugated synthetic peptide derived from human Mitofusin 2
Gene ID 9927
Swiss Prot O95140
Applications IF(IHC-P)
Applications with corresponding dilutions IF(IHC-P)(1:50-200)
Cross reactive species Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
Cross Reactive Species details No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
Background information Essential transmembrane GTPase, which mediates mitochondrial fusion. Fusion of mitochondria occurs in many cell types and constitutes an important step in mitochondria morphology, which is balanced between fusion and fission. MFN2 acts independently of the cytoskeleton. It therefore plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Overexpression induces the formation of mitochondrial networks. Plays an important role in the regulation of vascular smooth muscle cell proliferation. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Is required for PARK2 recruitment to dysfunctional mitochondria. Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress. Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions.
Purification method Purified by Protein A.
Storage Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Excitation emission 590nm/617nm
Synonyms HSG; MARF; CMT2A; CPRP1; CMT2A2; Mitofusin-2; Transmembrane GTPase MFN2; MFN2; KIAA0214
Also known as Mitofusin 2 Polyclonal Antibody
Other name Anti-Mitofusin 2 Polyclonal
Advisory Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Properties For facs or microscopy Alexa 1 conjugate.
Conjugation Alexa Fluor,ALEXA FLUOR® 594
Conjugated Alexa conjugate 1
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Group Polyclonals and antibodies
About Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
Gene targetMitofusin
Short name Anti-Mitofusin 2
Technique Polyclonal, anti
Isotype Immunoglobulin G (IgG)
Label ALEXA FLUOR 594
Alternative name Mitofusin 2 Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
Alternative technique polyclonals
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Anti-Mitofusin 2 | Technique alternative | 01011199134
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