CEP-18770
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Catalog number2433-25
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PricePlease ask
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Size25 mg
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Alternative_name[(1R)-1-[[(2S,3R)-3-Hydroxy-2-[[(6-phenylpyridin-2-yl)carbonyl]amino]-1-oxobutyl]amino]-3-methylbutyl]boronic acid
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DescriptionCEP-18770 is a reversible P2 threonine boronic acid inhibitor of the chymotrypsin-like activity of the proteasome. Displays anti-multimyeloma (MM) effect.
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CAS Number847499-27-8
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₁H₂₈BN₃O₅
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Molecular Weight413.28
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (>70 mg/ml) or EtOH (>70 mg/ml)
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HandlingProtect from air and mositure
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Tag LineA potent proteosome inhibitor
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Storage Condition-20 ̊C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID24800541
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SMILESB(C(CC(C)C)NC(=O)C(C(C)O)NC(=O)C1=CC=CC(=N1)C2=CC=CC=C2)(O)O
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InChiInChI=1S/C21H28BN3O5/c1-13(2)12-18(22(29)30)24-21(28)19(14(3)26)25-20(27)17-11-7-10-16(23-17)15-8-5-4-6-9-15/h4-11,13-14,18-19,26,29-30H,12H2,1-3H3,(H,24,28)(H,25,27)/t14-,18+,19+/m1/s1
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InChi KeySJFBTAPEPRWNKH-CCKFTAQKSA-N
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MSDS AvailableYes
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Gene target
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Gene symbolCRTAC1
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Short nameCEP-18770
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Alternative nameCEP-18770
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Gene info
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Identity
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Gene
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Long gene namecartilage acidic protein 1
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Synonyms
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GenBank acession
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Locus
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Discovery year2001-05-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID