AAV-DJ/8 Helper Free Bicistronic Expression System (Hygro)

  • Catalog number
    VPK-417-DJ-8
  • Price
    Please ask
  • Size
    1 kit
  • Shipping Temp
    Blue Ice
  • Storage Temp
    -20ÂșC
  • Category Product Type
    Kit
  • URL link to SDS
    more (VPK-410 through VPK-430-SER6) GHS.pdf
  • UNSPSC
    41105908
  • Product Line
    Viral Expression
  • Short Description
    The AAV Helper Free System produces recombinant AAV containing your gene of interest without the need to use a helper adenovirus. The adenoviral genes required for proper AAV packaging are provided in the pHelper plasmid (E2A, E4 and VA RNA) or in the 293 packaging cells (E1). AAV Helper Free Complete Expression Systems are available for native serotypes 1 through 6, as well as the novel AAV-DJ and AAV-DJ/8. The AAV-DJ system provides a hybrid capsid created by DNA shuffling technology combining 8 different native serotypes: AAV-2, AAV-4, AAV-5, AAV-8, AAV-9, avian AAV, bovine AAV, and caprine AAV. The result is a highly infectious vector that can transduce a wide variety of cells and tissues at significantly higher rates than AAV-2. AAV-DJ/8 was created by making a point mutation in the heparin binding domain of AAV-DJ. Recombinant AAV produced from the AAV-DJ/8 system closely resembles AAV-8 and AAV-9 in its ability to infect heart and brain tissues.
  • Product feature 1
    Complete Expression System contains packaging plasmids, expression vector and GFP control vector
  • Product feature 2
    pHelper plasmid contains required E2A, E4, and VA RNA adenoviral genes; eliminates the need for a helper adenovirus
  • Product feature 3
    AAV-DJ/8 is a mutant of AAV-DJ designed to provide increased uptake in brain tissue, closely mimicking AAV-8 and AAV-9
  • Gene target
  • Gene symbol
    AAVS1, PATE3, PARK7, DNAJA1
  • Short name
    AAV-DJ/8 Helper Free Bicistronic Expression System (Hygro)
  • Alternative name
    AAV-DJ/8 Helper Free Bicistronic Expression System (Hygro)
Gene info
  • Identity
  • Gene
  • Long gene name
    adeno-associated virus integration site 1
  • Synonyms
  • GenBank acession
  • Locus
  • Discovery year
    1990-09-10
  • Entrez gene record
    17
  • Pubmed identfication
Gene info
Gene info
Gene info
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