Vitronectin, Human Plasma
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Catalog number
4087-100
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Price
Please ask
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Size
100 ug
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Synonyms
S- protein, Serum-spreading factor, V75
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Alternative_names
S- protein, Serum-spreading factor, V75
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Description
A glycoprotein promoting cell adhesion and spreading
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Recombinant
No
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Source
Human plasma
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Purity by SDS PAGE
≥95%
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Assay
SDS-PAGE
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Molecular Weight
75.0 kDa
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Storage Temp
-20°C
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Shipping
Gel pack
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Shelf Life
12 months
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Concentration
200 to 400 ug/ml
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Appearance
Lyophilized protein
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Physical form description
Lyophilized from 10 mM sodium phosphate, pH 7.7
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Reconstitution Instructions
Reconstitute in H₂O or aqueous buffers to a concentration not less than 0.1 mg/ml. Aliquot and store at –20°C. Avoid freeze-thaw cycles.
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Background Information
Vitronectin and plasminogen activator inhibitor type 1 are proteins that interact in the circulatory system and pericellular region to regulate fibrinolysis, cell adhesion, and migration. Plasminogen activator inhibitor type 1, a serine proteinase, through its binding to the plasma protein vitronectin, influences processes that are key regulators of hemostatic process, for example, thrombosis and wound healing. In addition, the vitronectin and plasminogen activator inhibitor type 1 complex regulates binding of blood platelets and cells to extracellular substrata in events like tumor metastasis. The plasma concentration of vitronectin is 200 to 400 ug/ml.
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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