SLK (Tyr530) Antibody, ALEXA FLUOR 350
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Catalog number
bs-5332R-A350
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Price
Please ask
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Size
100ul
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Long name
SLK (Tyr530) Polyclonal Antibody, ALEXA FLUOR 350 Conjugated
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Also known as
Anti-SLK Tyr530 PAb ALEXA FLUOR 350
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Category
Conjugated Primary Antibodies
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Conjugated with
ALEXA FLUOR® 350
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
SLK Tyr530
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Specificity
This is a highly specific antibody against SLK Tyr530.
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Modification
Phosphorylation
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Modification Site
Tyr530
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
KLH conjugated synthetic phosphopeptide derived from human FYN around the phosphorylation site of Tyr530
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Gene ID Number
2534
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the antigen
Fyn is a membrane-associated, non-receptor protein tyrosine kinase approximately 59kDa, which belongs to the Src family of cytoplasmic tyrosine kinases. Fyn is very strongly similar to mouse Fyn, v-yes and c-src. Fyn is expressed predominately in tissues of neuronal and hematopoietic origin. Neuronal Fyn and hematopoietic Fyn differ at the junction of the SH2 and kinase domains due to tissue specific alternative splicing. Fyn has been shown to be involved in B cell and T cell activation as well as keratinocyte differentiation. In T cells, Fyn associates with the T-cell antigen receptor and Thy1. The unique N terminal domain of Fyn interacts with the CD3 and eta chains of the TcR. Fyn can bind to other proteins (p82 and p116) through its SH2 and SH3 domains, which may act as substrates or regulators of Fyn activity. Fyn is highly expressed in brain suggesting that it may have a role in the sensory nervous network and in myelination at early stages of CNS formation.
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Purification
Purified by Protein A.
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Storage conditions
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
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Excitation emission
343nm/442nm
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Synonyms
Fyn phospho Y530; p-Fyn phospho Y530; C syn protooncogene; FYN oncogene related to SRC FGR YESï¼› MGC45350ï¼› OKT3 induced calcium influx regulatorï¼› P59 FYN; Protein tyrosine kinase fyn; Proto oncogene tyrosine protein kinase fyn; Protooncogene Syn; SLK; Src like kinase; Src yes related novel gene; Src/yes related novel gene; SYN; FYN; Tyrosine kinase p59fyn T; Tyrosine kinase p59fynT.
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Properties
For facs or microscopy Alexa 1 conjugate. Alexa Fluor 350 conjugates can be used in multi-color flow cytometry with FACS's equipped with a second red laser or red diode. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Conjugation
Alexa Fluor, ALEXA FLUOR 350
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French translation
anticorps
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Gene target
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Gene symbol
FYN, SLK
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Short name
Anti-SLK Tyr530
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Technique
Antibody, antibodies against human proteins, antibodies for
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Isotype
Immunoglobulin G (IgG)
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Label
ALEXA FLUOR 350
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Alternative name
SLK (Tyr530) Polyclonal Antibody, ALEXA FLUOR 350
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Alternative technique
antibodies
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Alternative to gene target
STE20-like kinase, bA16H23.1 and LOSK and se20-9 and STK2, SLK and IDBG-88663 and ENSG00000065613 and 9748, transferase activity, Cytoplasm, Slk and IDBG-174800 and ENSMUSG00000025060 and 20874, SLK and IDBG-639375 and ENSBTAG00000001017 and 535342
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Gene info
Gene info
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Identity
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Gene
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Long gene name
STE20 like kinase
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Synonyms gene name
- SNF1 (sucrose nonfermenting, yeast, homolog)-like kinase, SNF1 sucrose nonfermenting like kinase (yeast)
- STE20-like kinase (yeast)
- STE20-like kinase
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Synonyms
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Locus
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Discovery year
1992-04-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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