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anti Caspase 9 Antibody

anti Caspase 9 Antibody is available 5 times from Biovision labs

3149-100 | anti-Caspase-9 (Active) Antibody size: Caspase-9 (Active) Antibody | 561.30 USD

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3136-100 | anti-Caspase-9 Antibody size: Caspase-9 Antibody | 378.19 USD

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3409-100 | anti-Caspase-9 Antibody size: Caspase-9 Antibody | 378.19 USD

Catalog number 3409-100
Supplier Biovision
Price 378.19 USD
Size Caspase-9 Antibody
Target of this antibody: Caspase-9
Alternative names of antibody target: CASP-9 , EC 3.4.22.62 , ICE-like apoptotic protease 6 ,ICE-LAP6 ,Apoptotic protease Mch-6 ,Apoptotic protease-activating factor 3 , Apaf-3
Background information: Caspase-9 is one of the most important caspases among the caspase family members. Upon induction of apoptosis, cytochrome c released from mitochondria associates with procaspase-9/Apaf-1. The complex processes procaspase-9 into a large subunit (35 kDa or 17 kDa) and small (10 kDa) by self-cleavage at D315. Activated caspase-9 further cleaves other caspase members including caspase-3, one of the proteases responsible for the proteolytic cleavage of many key proteins in apoptosis. In addition to self-cleavage, procaspase-9 can also be cleaved in vivo by caspase-3 at D330. The process served as a positive feedback to amplify the apoptotic signal in caspase activation pathway.
This antibody reacts with: Mouse, rat
Immunogene sequence: Synthetic peptide surrounding amino acid 345 of mouse caspase-9
Concentration of antibody: 0.2 mg/ml
Formulation of this antibody: 100 µg (0.2 mg/ml) protein A purified rabbit anti-caspase-9 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification method: Affinity purified
This antibody has been succesfully tested for use in following methods: Western blot
Recommended usage: Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Mouse small intestine and rat kidney tissue lysates can be used as positive controls. The antibody detects 45 kDa procaspase-9, 35/37 kDa cleaved large fragment and the 25 kDa fully cleaved caspase-9.
Gene targetCaspase-9
Short name anti-Caspase-9 Antibody
Alternative name antibody to-caspase-9 (Antibody to)
1. Gene info
Identity 1511
Gene CASP9
Long gene name caspase 9
Synonyms gene name
  • caspase 9, apoptosis-related cysteine protease
  • caspase 9, apoptosis-related cysteine peptidase
Synonyms
  • MCH6
  • ICE-LAP6
  • APAF-3
  • PPP1R56
Synonyms name
  • protein phosphatase 1, regulatory subunit 56
GenBank acession
  • U60521
Locus 1p36.21
Discovery year 1996-11-11
Entrez gene record 842
Pubmed identfication
  • 8663294
  • 9390557
RefSeq identity
  • NM_032996
Classification
  • Caspases
  • Protein phosphatase 1 regulatory subunits
  • Caspase recruitment domain containing
  • Apoptosome
Havana BLAST/BLAT OTTHUMG00000002256
Product images
    #0#.jpegCaspase-9 Antibody

6670-100 | anti-Caspase-9 Antibody size: Caspase-9 Antibody | 404.52 USD

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6670-30T | anti-Caspase-9 Antibody size: Caspase-9 Antibody | 175.93 USD

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Antibody host: Rabbit
Clonality of antibody: Polyclonal
Isotype: Rabbit IgG
Form of antibody: Liquid
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
How to handle this antibody: The antibody solution should be gently mixed before use.
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Human and some mouse caspases are active in apoptosis and cell death and even in necrosis and inflammation. CASP Gene and orthologous enzymes have been identifies successfully in the signal transduction cascade and pathways.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Technique Antibody, anti
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