Conjugated Primary Antibodies
Rabbit (Oryctolagus cuniculus)
This is a highly specific antibody against FANCD2.
1ug per 1ul
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FANCD2
Gene ID Number
Human, Mouse, Rat
Cross-reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen
Fanconi Anemia (FANC) is a human autosomal-recessive cancer susceptibility disorder characterized by congenital defects, progressive bone marrow failure, and cellular hypersensitivity to mitomycin C (MMC). The FANC subunit D2 protein is vital for cellular resistance to DNA cross-linking and the arrest of DNA synthesis after ionizing radiation.DNA damage activates the monoubiquitination of FANC D2, targeting nuclear foci containing the BRCA 1 protein.
Purified by Protein A.
Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
FA 4; FA D2; FA4; FAC D2; FACD 2; FACD; FACD2; FAD; FAD2; FANC D2; FANCD 2; FANCD; Protein FACD2; Type 4 Fanconi pancytopenia; FACD2_HUMAN; Fanconi anemia group D2 protein; Protein FACD2.
Immunoglobulin G (IgG)
Alternative to gene target
Fanconi anemia, complementation group D2, FA-D2 and FA4 and FACD and FAD and FAD2 and FANCD, FANCD2 and IDBG-17539 and ENSG00000144554 and 2177, DNA polymerase binding, nuclei, Fancd2 and IDBG-177677 and ENSMUSG00000034023 and 211651, FANCD2 and IDBG-644629 and ENSBTAG00000010077 and 515845