DMAP1 Antibody

• Catalog number
  3715-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  DMAP-1
• Target Alternative Name
  DNMAP 1 , DNMAP1 , EAF 2 , EAF2 , FLJ11543 , KIAA1425 , mgC55593 , SWC 4 , SWC4 , zgc:55593
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, mouse, rat
• Immunogen Sequence
  Synthetic peptide surrounding amino acid 438 of mouse DMAP1
• Accession
  Q9JI44
• Gene Id
  66233
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 1% BSA and 0.02% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot
• Application And Usages
  Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. Jurkat cell lysate (Cat.# 2401-100) and mouse small intestine tissue lysate (Cat.2601-100) can be used as positive controls. The antibody recognizes the DMAP1 of human, mouse and rat origins. Reactivity to other species has not been tested.
• Description
  DNA methylation can help regulate transcriptional silencing via repressive transcription complexes, which include methyl-CpG-binding domain protein and Histone deacetylases (HDACs) DNMT1. This core enzyme for mammalian DNA methylation can also establish a repressive transcription complex consisting of DNMT1, HDAC2 and DMAP1. DMAP1 can interact directly with the transcriptional corepressor TSG101. The DNMT1-DMAP1 exists throμghout the S-phase; HDAC2 joind DNMT1 and DMAP1 only during Late S phase. This provides a regulated means to deacetylate heterochromatin following replication
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  DMAP1  
• Gene symbol
  DMAP1
• Short name
  DMAP1 Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  DMAP1 (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:18291
• Gene
  DMAP1
• Long gene name
  DNA methyltransferase 1 associated protein 1
• Synonyms
  • DNMAP1
  • FLJ11543
  • KIAA1425
  • DNMTAP1
  • EAF2
  • MEAF2
  • SWC4
• GenBank acession
  • AB037846
• Locus
  1p34.1
• Discovery year
  2003-03-12
• Entrez gene record
  55929
• Pubmed identfication
  • 10888872
  • 10718198
• RefSeq identity
  • NM_019100
• Classification
  • Myb/SANT domain containing
  • SRCAP complex
• VEGA ID
  OTTHUMG00000007577

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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