This antibody has been succesfully tested for use in following methods:
Target of this antibody:
Formulation of this antibody:
PBS with 0.09% (W/V) sodium azide.
Alternative names of antibody target:
CD160 antigen, Natural killer cell receptor BY55, CD160, CD160, BY55
Shelf time: 12 months in temp.: -20 deg.C
This antibody reacts with:
Clonality of antibody:
Protein A column, followed by peptide affinity purification.
KLH conjugated synthetic peptide between 56-82 amino acids from the Central region of human CD160.
How to handle this antibody:
The antibody solution should be gently mixed before use
CD160 is a 27 kDa glycoprotein which was initially identified with the monoclonal antibody BY55. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. The cDNA sequence of CD160 predicts a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain weakly homologous to KIR2DL4 molecule. CD160 is expressed at the cell surface as a tightly disulfide-linked multimer. RNA blot analysis revealed CD160 mRNAs of 1.5 and 1.6 kb whose expression was highly restricted to circulating NK and T cells, spleen and small intestine. Within NK cells CD160 is expressed by CD56dimCD16+ cells whereas among circulating T cells its expression is mainly restricted to TCRgd bearing cells and to TCRab+CD8brightCD95+ CD56+CD28-CD27-cells. In tissues, CD160 is expressed on all intestinal intraepithelial lymphocytes. CD160 shows a broad specificity for binding to both classical and nonclassical MHC class I molecules.
Form of antibody:
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Polyclonals and antibodies
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
anti-CD160 Polyclonal Antibody
Polyclonal, Antibody, anti
antibody to-CD160 molecule polyclonal (Antibody to)
Alternative to gene target
CD160 molecule, BY55 and NK1 and NK28, CD160 and IDBG-101772 and ENSG00000117281 and 11126, MHC class I receptor activity, Plasma membranes, Cd160 and IDBG-176450 and ENSMUSG00000038304 and 54215