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anti-Apaf-1 Antibody

anti-Apaf-1 Antibody is available 1 time from Biovision labs

3018-100 | anti-Apaf-1 Antibody size: Apaf-1 Antibody | 378.80 USD

Catalog number 3018-100
Supplier Biovision
Price 378.80 USD
Size Apaf-1 Antibody
1. Gene info
Identity576
GeneAPAF1
Synonyms gene name
  • apoptotic protease activating factor
  • apoptotic peptidase activating factor
Synonyms
GenBank acession
Locus12q23.1
Discovery year1998-01-20
Pubmed identfication
RefSeq identity
Havana BLAST/BLATOTTHUMG00000170214
MeSH Data
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Product images
    #0#.jpegApaf-1 Antibody
This antibody has been succesfully tested for use in following methods: Western blot
Target of this antibody: Apaf-1
Formulation of this antibody: 100 µg (0.2 mg/ml) immunoaffinity purified, rabbit anti-Apaf-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.05% BSA, 0.01% thimerosal.
Alternative names of antibody target: APAF1, CED4, DKFZp781B1145, KIAA0413
Recommended usage: Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The immunoaffinity purified antibody detects a 130 kDa protein, corresponding to the apparent molecular weight of Apaf-1 on SDS-PAGE immunoblots.
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
Antibody host: Rabbit
This antibody reacts with: Human, mouse, rat, bovine, rabbit, monkey, horse
Clonality of antibody: Polyclonal
Isotype: Rabbit IgG
Purification method: Affinity purified
Immunogene sequence: Synthetic peptide surrounding amino acid 1161 of human Apaf-1
How to handle this antibody: The antibody solution should be gently mixed before use.
Background information: During apoptosis, Apaf-1 (apoptosis protease activating factor 1) binds to cytochrome c (Apaf-2), a reaction that requires dATP, and this leads to the formation of a large multimeric complex. The complex recruits pro-caspase-9, and activates caspase-9 (Apaf-3). Activated caspase-9 in turn cleaves and activates caspase-3, one of the proteases responsible for the proteolytic cleavage of many key proteins in apoptosis. Apaf-1 is ubiquitously expressed in human tissues.
Form of antibody: Liquid
Concentration of antibody: 0.2 mg/ml
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetApaf-1
Short name anti-Apaf-1 Antibody
Technique Antibody, anti
Alternative name antibody to-Apoptotic protease activating factor-1 (Antibody to)
Alternative technique antibodies
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