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anti Cathepsin Antibody

anti Cathepsin Antibody is available 19 times from Biovision labs

3190-100 | anti-Cathepsin B Antibody size: Cathepsin B Antibody | 400.73 USD

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3191R-100 | anti-Cathepsin D Antibody size: Cathepsin D Antibody | 374.65 USD

Catalog number 3191R-100
Supplier Biovision
Price 374.65 USD
Size Cathepsin D Antibody
Target of this antibody: Cathepsin D
Alternative names of antibody target: CTSD , CLN10, CPSD, MGC2311
Background information: Cathepsin D is a normal lysosomal protease that is expressed in all cells. It is an aspartyl protease with a pH optimum in the range of 3-5, and contains two N-linked oligosaccharides. Cathepsin D is synthesized as an inactive 52 kDa pro-enzyme. Activation involves the proteolytic removal of the 43 amino acid profragment and an internal cleavage to generate the two-chain form made up of 34 and 14 kDa subunits. Cathepsin D contains the mannose-6-phosphate lysosomal localization signal that targets the enzyme to the lysosomal compartment where it functions in the normal degradation of proteins. In certain tumor cells, Cathepsin D is abnormally processed and is secreted in its 52 kDa precursor form. Numerous clinical studies as well as in vitro evidence sμggest that cathepsin D plays an important role in malignant transformation and may be a useful prognostic indicator for breast cancer.
Antibody host: Rabbit
Clonality of antibody: Polyclonal
Isotype: Rabbit IgG
This antibody reacts with: Human, mouse, rat
Immunogene sequence: Synthetic peptide surrounding amino acid 140 of mouse cathepsins D
Concentration of antibody: 0.5 mg/ml
Formulation of this antibody: 100 µg (0.5 mg/ml) affinity purified rabbit anti-cathepsin D polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification method: Affinity purified
This antibody has been succesfully tested for use in following methods: Western blot
Recommended usage: Western blot analysis (0.5-4 µg/ml) and in immunoprecipitation. However, the optimal conditions should be determined individually. The purified antibody detects both the 52 kDa proform and the 34 kDa cleaved fragment of Cathepsin D.
Gene targetCathepsin
Short name anti-Cathepsin D Antibody
Alternative name antibody to-Cathepsin D (Antibody to)
1. Gene info
Identity 2529
Gene CTSD
Long gene name cathepsin D
Synonyms gene
  • CPSD
Synonyms gene name
  • cathepsin D (lysosomal aspartyl protease)
Synonyms
  • CLN10
Synonyms name
  • ceroid-lipofuscinosis, neuronal 10
GenBank acession
  • M11233
Locus 11p15.5
Discovery year 1986-01-01
Entrez gene record 1509
Pubmed identfication
  • 3927292
RefSeq identity
  • NM_001909
Classification
  • Cathepsins
Havana BLAST/BLAT OTTHUMG00000044760
Locus Specific Databases
  • Neuronal Ceroid Lipofuscinoses; NCL Mutations
Product images
    #0#.jpegCathepsin D Antibody

3371-100 | anti-Cathepsin F Antibody size: Cathepsin F Antibody | 400.73 USD

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3370-200 | anti-Cathepsin G Antibody size: Cathepsin G Antibody | 426.82 USD

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3367-100 | anti-Cathepsin H Antibody size: Cathepsin H Antibody | 400.73 USD

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3368-100 | anti-Cathepsin K Antibody size: Cathepsin K Antibody | 374.65 USD

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3588-100 | anti-Cathepsin K Antibody size: Cathepsin K Antibody | 439.86 USD

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3368-30T | anti-Cathepsin K Antibody size: Cathepsin K Antibody | 174.28 USD

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3741-100 | anti-Cathepsin L (Cleaved) Antibody size: Cathepsin L (Cleaved) Antibody | 374.65 USD

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6669-30T | anti-Cathepsin L Antibody size: Cathepsin L Antibody | 174.28 USD

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6669-100 | anti-Cathepsin L Antibody size: Cathepsin L Antibody | 400.73 USD

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3192-100 | anti-Cathepsin L Antibody size: Cathepsin L Antibody | 374.65 USD

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6686-100 | anti-Cathepsin S Antibody size: Cathepsin S Antibody | 400.73 USD

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3366R-100 | anti-Cathepsin S Antibody size: Cathepsin S Antibody | 374.65 USD

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3366-100 | anti-Cathepsin S Antibody size: Cathepsin S Antibody | 477.80 USD

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6686-30T | anti-Cathepsin S Antibody size: Cathepsin S Antibody | 174.28 USD

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3712-100 | anti-Cathepsin V Antibody size: Cathepsin V Antibody | 374.65 USD

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3411-100 | anti-Cathepsin V Antibody (Clone BV55-1) size: Cathepsin V Antibody (Clone BV55-1) | 439.86 USD

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3412-100 | anti-Cathepsin W Antibody (Clone BV39-2B) size: Cathepsin W Antibody (Clone BV39-2B) | 439.86 USD

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Form of antibody: Liquid
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
How to handle this antibody: The antibody solution should be gently mixed before use.
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Gene CTS protease activity also measured by zymograph electrophoresis of Cathepsins. This cathepsin is supplied in 1.
French translation anticorps
Technique Antibody, anti
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anti-Cathepsin D Antibody | Technique alternative | 01012191
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