CD18, phosphorylated (Ser745) (Beta 2 antigen CD18 (p95), Cell surface adhesion glycoproteins LFA 1/CR3/p150 95 beta subunit, Complement receptor C3 beta subunit, Integrin beta 2, ITGB2, LAD, LCAMB, Leukocyte Cell Adhesion Molecule CD18, LFA1, Lymphocyte Antibody

• Catalog number
  GEN608951
• Price
  Please ask
• Size
  100ul

• Also known as
  CD18
• Other names
  CD18; N/A; CD18; N/A; N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  LOC100304487; N/A; N/A; N/A
• Gene name synonims
  LOC100304487; N/A; N/A; N/A
• Other gene names
  LOC100304487; N/A; N/A; N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG
• Clone
  9H331
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes human LFA-beta2 when phosphorylated at Ser745. Species Crossreactivity: Mouse and rat. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Supernatant
• Form Appearance
  Supplied as a liquid in 50mM Tris-Glycine, pH 7.4, 0.15M sodium chloride, 40% glycerol, 0.01% sodium azide, 0.05% BSA.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. Long-term storage should be done after aliquoting the antibody and freezing the aliqotes at -20 degrees Celsius. Under these conditions the aliquots will be stable for at least one year if kept at -20 °C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
• Tested applications
  Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunocytochemistry (ICC)
• Description
  cell adhesion molecules play a role in cell growth and activation and are often identified by WB or ELISA as in the CD18, phosphorylated (Ser745) (Beta 2 antigen CD18 (p95), surface adhesion glycoproteins LFA 1/CR3/p150 95 beta subunit, Complement receptor C3 beta subunit, Integrin beta 2, ITGB2, LAD, LCAMB, Leukocyte Adhesion Molecule CD18, LFA1, Lymphocyte Antibody. Antigens are peptides or recombinant or native dependent on the production method. For cells, cell lines and tissues in culture till half confluency. Whole adhesion and interacting molecules are  present in lysates used as reference for ELISA quantification of these molecules and their subunits. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  CD18   phosphorylated   Ser745   Beta   CD18   p95   surface   adhesion   glycoproteins   LFA   1/CR3/p150   beta   subunit   Complement   receptor   beta   subunit   Integrin   beta   ITGB2   LAD   LCAMB   Leukocyte   Adhesion   Molecule   CD18   LFA1   Lymphocyte  
• Gene symbol
  ITGB2, ITGB2-AS1, ITGAL, DLD
• Short name
  CD18, phosphorylated (Ser745) (Beta 2 antigen CD18 (p95), surface adhesion glycoproteins LFA 1/CR3/p150 95 beta subunit, Complement receptor C3 beta subunit, Integrin beta 2, ITGB2, LAD, LCAMB, Leukocyte Adhesion Molecule CD18, LFA1, Lymphocyte Antibody
• Technique
  Antibody, antigen, antibodies against human proteins, antibodies for, antigenes
• Alternative name
  Anti-CD18, phosphorylated (Ser745) (Beta 2 antigen CD18 (p95), Cell surface adhesion glycoproteins LFA 1/CR3/p150 95 beta subunit, Complement receptor C3 beta subunit, Integrin beta 2, ITGB2, LAD, LCAMB, Leukocyte Cell Adhesion Molecule CD18, LFA1, Lymphocyte
• Alternative technique
  antibodies, antigenes
• Alternative to gene target
  integrin, beta 2 (complement component 3 receptor 3 and 4 subunit), CD18 and LAD and LCAMB and LFA-1 and MAC-1 and MF17 and MFI7, ITGB2 and IDBG-5590 and ENSG00000160255 and 3689, metal ion binding, Cell surfaces, ITGB2 and IDBG-639611 and ENSBTAG00000017060 and 281877
• Tissue
  cell, lymphocyte

Gene info

• Identity
  HGNC:6155
• Gene
  ITGB2
• Long gene name
  integrin subunit beta 2
• Synonyms gene
  • CD18
  • MFI7
• Synonyms gene name
  • integrin, beta 2 (antigen CD18 (p95), lymphocyte function-associated antigen 1; macrophage antigen 1 (mac-1) beta subunit)
  • integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
• Synonyms
  • LFA-1
  • MAC-1
• Synonyms name
  • complement component 3 receptor 3 and 4 subunit
• GenBank acession
  • AK222505
• Locus
  21q22.3
• Discovery year
  1986-01-01
• Entrez gene record
  3689
• RefSeq identity
  • NM_000211
• Classification
  • Integrin beta subunits
  • Complement system regulators and receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000090257
• Locus Specific Databases
  • ITGB2base: Mutation registry for Leukocyte adhesion deficiency I (LAD-I)
  • LRG_76

Gene info

• Identity
  HGNC:44304
• Gene
  ITGB2-AS1
• Long gene name
  ITGB2 antisense RNA 1
• Synonyms gene name
  • ITGB2 antisense RNA 1 (non-protein coding)
• GenBank acession
  • BC040064
  • BC051807
• Locus
  21q22.3
• Discovery year
  2012-08-08
• Entrez gene record
  100505746
• RefSeq identity
  • NR_038311
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000090253

Gene info

• Identity
  HGNC:6148
• Gene
  ITGAL
• Long gene name
  integrin subunit alpha L
• Synonyms gene
  • CD11A
• Synonyms gene name
  • integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
• Synonyms
  • LFA-1
  • LFA1A
• Synonyms name
  • antigen CD11A (p180)
  • lymphocyte function-associated antigen 1, alpha polypeptide
• Locus
  16p11.2
• Discovery year
  1986-01-01
• Entrez gene record
  3683
• Pubmed identfication
  • 3284962
• Classification
  • Integrin alpha subunits
  • CD molecules
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000176964

Gene info

• Identity
  HGNC:2898
• Gene
  DLD
• Long gene name
  dihydrolipoamide dehydrogenase
• Synonyms gene
  • LAD
  • GCSL
• Synonyms gene name
  • dihydrolipoamide dehydrogenase (E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex)
• Synonyms
  • DLDH
  • E3
  • OGDC-E3
• Synonyms name
  • E3 component of pyruvate dehydrogenase complex, 2-oxo-glutarate complex, branched chain keto acid dehydrogenase complex
• GenBank acession
  • AB209703
• Locus
  7q31.1
• Discovery year
  1988-05-11
• Entrez gene record
  1738
• RefSeq identity
  • NM_000108
• Classification
  • Pyruvate dehydrogenase complex
• VEGA ID
  OTTHUMG00000154813

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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