Anti-5HT3A Receptor/SR-3A (Polyclonal), ALEXA Fluor 594
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Catalog numberGENTObs-12051R-A594
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PricePlease ask
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Size100 microliters
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TypeConjugated Primary Antibody
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Conjugated withALEXA FLUOR® 594
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Host organismRabbit (Oryctolagus cuniculus)
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Target Protein Peptide5HT3A Receptor/SR-3A
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SpecificityThis antibody reacts specifically with 5HT3A Receptor/SR-3A
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ModificationNo modification has been applied to this antibody
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Modification siteNone
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ClonalityPolyclonal Antibody
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ClonePolyclonal Antibodies
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Concentration1ug per 1ul
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Subcellular locationsExtracellular
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Antigen SourceKLH conjugated synthetic peptide derived from human 5HT3A Receptor/SR-3A
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Gene ID3359
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Swiss ProtP46098
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ApplicationsIF(IHC-P)
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Applications with corresponding dilutionsIF(IHC-P)(1:50-200)
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Cross reactive speciesHuman (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
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Cross Reactive Species detailsNo significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
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Background informationThis is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor is a ligand-gated ion channel, which when activated causes fast, depolarizing responses in neurons. It is a cation-specific, but otherwise relatively nonselective, ion channel.
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Purification methodPurified by Protein A.
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StorageWater buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
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Excitation emission590nm/617nm
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SynonymsHTR3; 5HT3R; 5-HT-3; 5-HT3A; 5-HT3R; 5-hydroxytryptamine receptor 3A; 5-HT3-A; 5-hydroxytryptamine receptor 3; Serotonin receptor 3A; Serotonin-gated ion channel receptor; HTR3A
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Also known as5HT3A Receptor/SR-3A Polyclonal Antibody
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Other nameAnti-5HT3A Receptor/SR-3A Polyclonal
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AdvisoryAvoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
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PropertiesFor facs or microscopy Alexa 1 conjugate.
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ConjugationAlexa Fluor, ALEXA FLUOR® 594
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ConjugatedAlexa conjugate 1
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use. The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
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GroupPolyclonals and antibodies
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AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
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Gene target
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Gene symbolMSR1, IGHD3OR15-3A, H3-3A-DT, MEGF10, MARCO, SRPRB, SIGMAR1, SNCG, H3-3A, FAM102A
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Short nameAnti-5HT3A Receptor/SR-3A
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TechniquePolyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
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IsotypeImmunoglobulin G (IgG)
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LabelALEXA FLUOR 594
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Alternative name5HT3A Receptor/SR-3A Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
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Alternative techniquepolyclonals, antibodies
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Gene info
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Identity
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Gene
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Long gene namemacrophage scavenger receptor 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1991-08-07
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Pubmed identfication
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Classification
- CD molecules
- Scavenger receptors
- Scavenger receptor cysteine rich domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy diversity 3/OR15-3A (non-functional)
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Synonyms gene name
- immunoglobulin heavy diversity 3/OR15-3A
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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Pubmed identfication
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Classification
- Immunoglobulin heavy (IGH) orphons
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameH3-3A divergent transcript
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Locus
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Discovery year2020-08-21
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Classification
- Divergent transcripts
Gene info
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Identity
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Gene
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Long gene namemultiple EGF like domains 10
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Synonyms gene name
- multiple EGF-like-domains 10
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Synonyms
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GenBank acession
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Locus
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Discovery year2006-03-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Scavenger receptors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemacrophage receptor with collagenous structure
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-11-26
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Scavenger receptors
- Scavenger receptor cysteine rich domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameSRP receptor subunit beta
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Synonyms gene name
- signal recognition particle receptor, B subunit
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-01-29
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Entrez gene record
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Pubmed identfication
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesigma non-opioid intracellular receptor 1
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Synonyms gene
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Synonyms gene name
- opioid receptor, sigma 1
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-03-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesynuclein gamma
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1998-04-07
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Entrez gene record
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Pubmed identfication
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameH3.3 histone A
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Synonyms gene
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Synonyms gene name
- H3 histone, family 3A
- H3 histone family member 3A
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Synonyms
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GenBank acession
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Locus
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Discovery year1989-12-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- H3 histones
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namefamily with sequence similarity 102 member A
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Synonyms gene
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Synonyms gene name
- chromosome 9 open reading frame 132
- family with sequence similarity 102, member A
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Synonyms
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Synonyms name
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Locus
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Discovery year2005-03-22
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Entrez gene record
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Pubmed identfication
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Classification
- NT-C2 domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data