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UNC 1215 for cell activation

UNC 1215 for cell activation is available 2 times from Biovision labs

2252-1 | UNC 1215 for cell activation size: 1 mg | 136.79 USD

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2252-5 | UNC 1215 for cell activation size: 5 mg | 333.50 USD

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Other name (2-​(Phenylamino)-​1,​4-​phenylene)bis((4-​(pyrrolidin-​1-​yl)piperidin-​1-​yl)methanone
Supplied with N/A
Description Cell-permeable. A potent and selective chemical probe for the methyllysine (Kme) reading function of L3MBTL3, a member of the malignant brain tumor (MBT) family of chromatin-interacting transcriptional repressors. It binds L3MBTL3 with a Kd value of 120 nM (IC₅₀ = 40 nM), competitively displacing mono- or dimethyl-lysine containing peptides. UNC1215 is > 50-fold selective toward L3MBTL3 than other members of the human MBT family and demonstrates selectivity against more than 200 other Kme reader domains examined.
Category Biochemicals
Molecular formula C₃₂H₄₃N₅O₂
Is it cell-permeable? Yes
Molecular weight 529.72
Storage condition -20°C
Shipping condition gel pack
Purification ≥98% by HPLC
Peptide sequence N/A
Is this a salt? No
CAS number 1415800-43-9
Storage instructions Protect from light and moisture
Maximum time for storage 24 months
Physical appearance White to Off-white Solid
Reconstitute instructions DMSO (50 mM)
Additional description For cells, cell lines and tissues in culture till half confluency.
Gene targetUNC 1215 for activation
Short name UNC 1215 for activation
Technique activation
Alternative name UNC 1215 to measure cellular activation
Tissue cell
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