CDKN2B, CT (CDKN2B, MTS2, Cyclin-dependent kinase 4 inhibitor B, Multiple tumor suppressor 2, p14-INK4b, p15-INK4b)[CDKN2B]

• Catalog number
  MBS648300
• Price
  Please ask
• Size
  NA

• Products_type
  Antibody
• Reactivity
  Human
• Description
  Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme. Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.

• Gene target
  CDKN2B   CDKN2B   MTS2   Cyclin-dependent   kinase   inhibitor   Multiple   tumor   suppressor   p14-INK4b   p15-INK4b   [CDKN2B]  
• Gene symbol
  CDKN2B, CDKN2B-AS1
• Short name
  CDKN2B, CT (CDKN2B, MTS2, Cyclin-dependent kinase 4 inhibitor B, Multiple tumor suppressor 2, p14-INK4b, p15-INK4b)[CDKN2B]
• Host
  Rabbit
• Alternative name
  cyclin-dependent phosphorylation catalyst inhibitor 2B (p15, inhibits cyclin-dependent kinase 4), CT (cyclin-dependent phosphorylation catalyst inhibitor 2B (p15, inhibits cyclin-dependent kinase 4), MTS2, Cyclin-dependent phosphorylation catalyst 4 suppressor B, Multiple tumor suppressor 2, p14-INK4b, p15-INK4b)[cyclin-dependent phosphorylation catalyst inhibitor 2B (p15, inhibits cyclin-dependent kinase 4)]
• Alternative to gene target
  cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4), CDK4I and INK4B and MTS2 and P15 and p15INK4b and TP15, CDKN2B and IDBG-54658 and ENSG00000147883 and 1030, protein kinase binding, nuclei, Cdkn2b and IDBG-162957 and ENSMUSG00000073802 and 12579, BT.45725 and IDBG-630040 and ENSBTAG00000016412 and 527124
• Tissue
  tumor

Gene info

• Identity
  HGNC:1788
• Gene
  CDKN2B
• Long gene name
  cyclin dependent kinase inhibitor 2B
• Synonyms gene name
  • cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
• Synonyms
  • P15
  • MTS2
  • INK4B
  • TP15
  • CDK4I
  • p15INK4b
• GenBank acession
  • AB060808
• Locus
  9p21.3
• Discovery year
  1995-06-14
• Entrez gene record
  1030
• Pubmed identfication
  • 8078588
• RefSeq identity
  • NM_004936
• VEGA ID
  OTTHUMG00000019691

Gene info

• Identity
  HGNC:34341
• Gene
  CDKN2B-AS1
• Long gene name
  CDKN2B antisense RNA 1
• Synonyms gene
  • CDKN2BAS
• Synonyms gene name
  • CDKN2B antisense RNA (non-protein coding)
• Synonyms
  • ANRIL
  • RP11-145E5.4
  • NCRNA00089
  • p15AS
  • CDKN2B-AS
  • PCAT12
• Synonyms name
  • antisense RNA in the INK4 locus
  • non-protein coding RNA 89
  • p15 antisense RNA
  • CDKN2B antisense RNA (non-protein coding)
  • prostate cancer associated transcript 12
• GenBank acession
  • BC038540
• Locus
  9p21.3
• Discovery year
  2008-11-25
• Entrez gene record
  100048912
• Pubmed identfication
  • 18048406
  • 17440112
  • 21532571
  • 23416462
• RefSeq identity
  • NR_003529
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000019689

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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