anti-AKT3 Antibody [66C1247.1]
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Catalog number48-641
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PricePlease ask
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Size0.05 mg
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Gene infoAkt, protein kinase B (PKB), is a serine/threonine kinase which is involved in many cellular signaling pathways and acts as a transducer of many functions initiated by growth factor receptors that activat phosphtidylinositol 3-kinase (PI 3-kinase). The major activity of Akt/PKB is to mediate cell survival. Akt/PKB is also believed to be a critical factor in the genesis of cancer as the tumor suppressor PTEN was found to antagonise PI-3 kinase and Akt/PKB kinase activity. There are 3 known isoforms of this enzyme in mammalian cells (1/alpha, 2/beta and 3/gamma). Akt1, 2 and 3 contain a key regulatory serine phosphorylation site in the carboxy-terminal region of the protein. Akt/PKB phosphorylation is critical for it activity.
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Gene namesAKT3, AKT3/PKBgamma, PRKBG, PKB gamma, Protein kinase Akt-3, RAC-gamma, MPPH, PKB-GAMMA, PKBG, Protein kinase B gamma, RAC-PK-gamma, STK-2
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Antibodie s labelunlabelled serum
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PurityProtein G Column
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Ab raised inMouse
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TypeMonoclonal
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Monoclonal[66C1247.1]
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ImmunoglobulinIgG1
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AntigenAKT3 monoclonal antibody was made against amino acids 119 - 136 of AKT3 (Human).
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Immuno applicationWestern Blot, immuno-histo-chemistry
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Antibody adviceAKT3 antibody can be used in ELISA starting at 1:10000, Western Blot starting at 1:500 - 1:2000, immunohistochemistry starting at 1:200, immunofluorescence starting at 1:200 - 1:1000, and flow cytometry starting at 1:200 - 1:400.
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Suspention pH azidePBS, 0.05% BSA, 0.05% sodium azide.
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Keep atStore AKT3 antibody at 4 grades C or -20 grades C. As with all antibodies avoid freeze/thaw cycles.
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Works withBat, Gibbon, Bovine, Chicken, Dog, Gorilla, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
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Omim nr12643943
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Ncbi nrQ9Y243
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Vial with antibodyin solution
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NCBI GENE nr10000
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GENE symbolAKT3
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Antigene namev-akt murine thymoma viral oncogene homolog 3
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SourceHomo sapiens
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Protein nrQ9Y243
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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PropertiesIf you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolAKT3-IT1, AKT3
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Short nameanti-AKT3 Antibody [66C1247 1]
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TechniqueAntibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
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Alternative nameAntibody toAKT3 (antibody to-) [66C1247.1]
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene nameAKT3 intronic transcript 1
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Synonyms gene name
- AKT3 intronic transcript 1 (non-protein coding)
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Locus
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Discovery year2011-05-20
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Classification
- Intronic transcripts
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameAKT serine/threonine kinase 3
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Synonyms gene name
- v-akt murine thymoma viral oncogene homolog 3
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-11-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Pleckstrin homology domain containing
- AKT kinases
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
