CCL21, human recombinant

• Catalog number
  7338-50
• Price
  Please ask
• Size
  50 ug

• Synonyms
  C-C motif chemokine 21, 6Ckine, CKb9, ECL, SCYA21, SLC, TCA4.
• Alternative_names
  C-C motif chemokine 21, 6Ckine, CKb9, ECL, SCYA21, SLC, TCA4.
• Description
  Inhibits hemopoiesis and stimulates chemotaxis
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥90%
• Assay
  SDS-PAGE
• Molecular Weight
  14.16 kDa
• Storage Temp
  -20°C
• Shipping
  Dry Ice
• Shelf Life
  12 months
• Appearance
  Liquid
• Physical form description
  0.5 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, and 1 mM DTT.
• Background Information
  CCL21 is member of the chemokine superfamily and the subfamily of CC chemokines that has an aspartate cysteine-cysteine-leucine motif near its amino-terminus. This protein is involved in inhibits hemopoiesis and stimulates chemotaxis. CCL21 is chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. It may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. Recombinant CCL21 protein was expressed in E.coli and purified by using conventional chromatography techniques.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CCL21  
• Gene symbol
  CCL21
• Short name
  CCL21, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  chemokine (C-C motif) ligand 21, H. sapiens Rec.
• Alternative technique
  rec
• Alternative to gene target
  chemokine (C-C motif) ligand 21, 6Ckine and CKb9 and ECL and SCYA21 and SLC and TCA4, CCL21 and IDBG-61074 and ENSG00000137077 and 6366, chemokine receptor binding, Extracellular, BT.26536 and IDBG-635977 and ENSBTAG00000010161 and 511112

Gene info

• Identity
  HGNC:10620
• Gene
  CCL21
• Long gene name
  C-C motif chemokine ligand 21
• Synonyms gene
  • SCYA21
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 21
  • chemokine (C-C motif) ligand 21
• Synonyms
  • SLC
  • exodus-2
  • TCA4
  • CKb9
  • 6Ckine
  • ECL
• Synonyms name
  • beta chemokine exodus-2
  • secondary lymphoid tissue chemokine
  • Efficient Chemoattractant for Lymphocytes
• GenBank acession
  • AB002409
• Locus
  9p13.3
• Discovery year
  1997-04-10
• Entrez gene record
  6366
• Pubmed identfication
  • 9235955
• RefSeq identity
  • NM_002989
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000019838

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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