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Anti-HER4 (Tyr1188) (Polyclonal), ALEXA Fluor 594

Anti-HER4 (Tyr1188) (Polyclonal), ALEXA Fluor 594 is available 1 time from Bioss polyclonal antibodies labs

GENTObs-5343R-A594 | Anti-HER4 (Tyr1188) (Polyclonal), ALEXA Fluor 594 size: 100 microliters | 585.87 USD

Catalog number GENTObs-5343R-A594
Price 585.87 USD
Size 100 microliters
1. Gene info
Identity3432
GeneERBB4
Synonyms gene name
  • v-erb-a avian erythroblastic leukemia viral oncogene homolog-like 4
  • v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4
Synonyms
GenBank acession
Locus2q34
Discovery year1995-09-07
Pubmed identfication
RefSeq identity
Havana BLAST/BLATOTTHUMG00000133012
MeSH Data
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Type Conjugated Primary Antibody
Conjugated with ALEXA FLUOR® 594
Host organism Rabbit (Oryctolagus cuniculus)
Target Protein/Peptide HER4 Tyr1188
Specificity This antibody reacts specifically with HER4 (Tyr1188)
Modification Phosphorylation
Modification site Tyr1188
Clonality Polyclonal Antibody
Clone Polyclonal Antibodies
Concentration 1ug per 1ul
Subcellular locations N/A
Antigen Source KLH conjugated synthetic phosphopeptide derived from human HER4 around the phosphorylation site of Tyr1188
Gene ID 2066
Swiss Prot N/A
Applications IF(IHC-P)
Applications with corresponding dilutions IF(IHC-P)(1:50-200)
Cross reactive species Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus)
Cross Reactive Species details No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
Background information This gene is a member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. It encodes a single-pass type I membrane protein with multiple cysteine rich domains, a transmembrane domain, a tyrosine kinase domain, a phosphotidylinositol-3 kinase binding site and a PDZ domain binding motif. The protein binds to and is activated by neuregulins and other factors and induces a variety of cellular responses including mitogenesis and differentiation. Multiple proteolytic events allow for the release of a cytoplasmic fragment and an extracellular fragment. Mutations in this gene have been associated with cancer. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008].
Purification method Purified by Protein A.
Storage Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
Excitation emission 590nm/617nm
Synonyms ErbB 4 phospho Y1188; p-ErbB 4 phospho Y1188; ErbB4; HER 4; HER4; Avian erythroblastic leukemia viral oncogene homolog 4; Avian erythroblastic leukemia viral v erb b2 oncogene homolog 4; MGC138404; P180erbB4; Receptor protein tyrosine kinase erbB 4 precursor; Receptor tyrosine protein kinase erbB 4;Tyrosine kinase type cell surface receptor HER4; v erb a avian erythroblastic leukemia viral oncogene homolog like 4; v erb a erythroblastic leukemia viral oncogene homolog 4; Verba avian erythroblastic leukemia viral oncogene homolog like 4; Verba erythroblastic leukemia viral oncogene homolog 4; VERBB2.
Also known as HER4 (Tyr1188) Polyclonal Antibody
Other name Anti-HER4 (Tyr1188) Polyclonal
Advisory Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Properties For facs or microscopy Alexa 1 conjugate.
Conjugation Alexa Fluor,ALEXA FLUOR® 594
Conjugated Alexa conjugate 1
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Group Polyclonals and antibodies
About Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
Gene targetHER4 Tyr1188
Short name Anti-HER4 (Tyr1188) (Polyclonal)
Technique Polyclonal, anti
Label ALEXA FLUOR 594
Alternative name antibody to-HER4 (Tyr1188) (polyclonal), ALEXA Fluor 594
Alternative technique polyclonals
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  • HER4
  • Tyr1188
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