Recombinant Human C-X-C Motif Chemokine 12/CXCL12/SDF-1 (22-89)

• Catalog number
  C121-1000
• Price
  Please ask
• Size
  1 mg

• Description
  Recombinant Human C-X-C Motif Chemokine 12 is produced by our E.coli expression system and the target gene encoding Lys22-Lys89 is expressed.
• Species reactivity
  Human
• Origin
  Escherichia coli
• Peptide sequence
  KPVSLSYRCPCRFFESHVARANVKHLKILNTPNCALQIVARLKNNNRQVCIDPKLKWIQEYLEKALNK
• Estimated molecular weight
  8,12 kDa
• Protein purity
  Greater than 95% as determined by reducing SDS-PAGE.
• Endotoxin level
  Less than 0.1 ng/µg (1 IEU/µg) as determined by LAL test.
• Shipping condition
  Ambient/Room Temperature
• Package form
  Lyophilized from a 0.2 µm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
• Storage conditions
  Lyophilized protein should be stored at below -20°C, though stable at room temperature for 3 weeks.Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at below -20°C for 3 months.
• Reconstitution conditions
  Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 µg/ml.Dissolve the lyophilized protein in ddH2O.Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• UniProt number
  P48061
• Other related products
• Additional description
  Chemokines, chemokine receptors, ligands , motif chemokines and cytokines are supplied by novo in 1.
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  C-X-C   Motif   Chemokine   12/CXCL12/SDF-1   22-89  
• Gene symbol
  CXCL12, SMC4, PFDN4, FOS, JUN, TAC4, MYB, PCK1, ROS1
• Short name
  Recombinant C-X-C Motif Chemokine 12/CXCL12/SDF-1 (22-89)
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. novo advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Human CXCL12/SDF-1(22-89)
• Alternative technique
  rec
• Alternative to gene target
  chemokine (C-X-C motif) ligand 12, IRH and PBSF and SCYB12 and SDF1 and TLSF and TPAR1, CXCL12 and IDBG-71595 and ENSG00000107562 and 6387, CXCR chemokine receptor binding, Extracellular, Cxcl12 and IDBG-180998 and ENSMUSG00000061353 and 20315, CXCL12 and IDBG-632037 and ENSBTAG00000005077 and 613811

Gene info

• Identity
  HGNC:10672
• Gene
  CXCL12
• Long gene name
  C-X-C motif chemokine ligand 12
• Synonyms gene
  • SDF1A
  • SDF1B
  • SDF1
• Synonyms gene name
  • stromal cell-derived factor 1
  • chemokine (C-X-C motif) ligand 12
• Synonyms
  • SCYB12
  • SDF-1a
  • SDF-1b
  • PBSF
  • TLSF-a
  • TLSF-b
  • TPAR1
• GenBank acession
  • L36033
• Locus
  10q11.21
• Discovery year
  1994-11-30
• Entrez gene record
  6387
• Pubmed identfication
  • 7490086
• RefSeq identity
  • NM_000609
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000018054

Gene info

• Identity
  HGNC:14013
• Gene
  SMC4
• Long gene name
  structural maintenance of chromosomes 4
• Synonyms gene
  • SMC4L1
• Synonyms gene name
  • SMC4 (structural maintenance of chromosomes 4, yeast)-like 1
  • SMC4 structural maintenance of chromosomes 4-like 1 (yeast)
• Synonyms
  • hCAP-C
  • CAP-C
• GenBank acession
  • AF092564
• Locus
  3q25.33
• Discovery year
  2001-02-22
• Entrez gene record
  10051
• Pubmed identfication
  • 9789013
  • 10319587
• Classification
  • Structural maintenance of chromosomes proteins
  • Condensin I subunits
  • Condensin II subunits
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000159006

Gene info

• Identity
  HGNC:8868
• Gene
  PFDN4
• Long gene name
  prefoldin subunit 4
• Synonyms gene name
  • prefoldin 4
• Synonyms
  • PFD4
  • C-1
  • C1
• GenBank acession
  • U41816
• Locus
  20q13.2
• Discovery year
  1998-08-06
• Entrez gene record
  5203
• Pubmed identfication
  • 9630229
  • 8744932
• RefSeq identity
  • NM_002623
• Classification
  • Prefoldin subunits
• VEGA ID
  OTTHUMG00000032775

Gene info

• Identity
  HGNC:3796
• Gene
  FOS
• Long gene name
  Fos proto-oncogene, AP-1 transcription factor subunit
• Synonyms gene name
  • v-fos FBJ murine osteosarcoma viral oncogene homolog
  • FBJ murine osteosarcoma viral oncogene homolog
• Synonyms
  • c-fos
  • AP-1
• GenBank acession
  • K00650
• Locus
  14q24.3
• Discovery year
  2001-06-22
• Entrez gene record
  2353
• Pubmed identfication
  • 16123044
  • 16055710
  • 15926923
• RefSeq identity
  • NM_005252
• Classification
  • Fos transcription factor family
  • Basic leucine zipper proteins
• VEGA ID
  OTTHUMG00000171774

Gene info

• Identity
  HGNC:6204
• Gene
  JUN
• Long gene name
  Jun proto-oncogene, AP-1 transcription factor subunit
• Synonyms gene name
  • v-jun avian sarcoma virus 17 oncogene homolog
  • jun oncogene
• Synonyms
  • c-Jun
  • AP-1
• GenBank acession
  • AY217548
• Locus
  1p32.1
• Discovery year
  1988-05-11
• Entrez gene record
  3725
• Pubmed identfication
  • 3194415
• RefSeq identity
  • NM_002228
• Classification
  • Basic leucine zipper proteins
  • Jun transcription factor family
• VEGA ID
  OTTHUMG00000008376

Gene info

• Identity
  HGNC:16641
• Gene
  TAC4
• Long gene name
  tachykinin precursor 4
• Synonyms gene name
  • tachykinin 4
• Synonyms
  • HK-1
  • Pptc
  • PPT-C
• Synonyms name
  • hemokinin
• GenBank acession
  • AF521560
• Locus
  17q21.33
• Discovery year
  2004-10-20
• Entrez gene record
  255061
• Pubmed identfication
  • 11062498
  • 12383518
• RefSeq identity
  • NM_170685
• Classification
  • Tachykinin precursors
• VEGA ID
  OTTHUMG00000161830

Gene info

• Identity
  HGNC:7545
• Gene
  MYB
• Long gene name
  MYB proto-oncogene, transcription factor
• Synonyms gene name
  • v-myb avian myeloblastosis viral oncogene homolog
• Synonyms
  • c-myb
• Locus
  6q23.3
• Discovery year
  2001-06-22
• Entrez gene record
  4602
• Pubmed identfication
  • 17599807
• Classification
  • Myb/SANT domain containing
• VEGA ID
  OTTHUMG00000015629
• Locus Specific Databases
  • The Globin Gene Server

Gene info

• Identity
  HGNC:8724
• Gene
  PCK1
• Long gene name
  phosphoenolpyruvate carboxykinase 1
• Synonyms gene name
  • phosphoenolpyruvate carboxykinase 1 (soluble)
• Synonyms
  • PEPCK-C
• Locus
  20q13.31
• Discovery year
  1990-09-10
• Entrez gene record
  5105
• Pubmed identfication
  • 1492743
• VEGA ID
  OTTHUMG00000032825

Gene info

• Identity
  HGNC:10261
• Gene
  ROS1
• Long gene name
  ROS proto-oncogene 1, receptor tyrosine kinase
• Synonyms gene name
  • v-ros avian UR2 sarcoma virus oncogene homolog 1
  • v-ros UR2 sarcoma virus oncogene homolog 1 (avian)
  • c-ros oncogene 1 , receptor tyrosine kinase
• Synonyms
  • MCF3
  • ROS
  • c-ros-1
• GenBank acession
  • M13599
• Locus
  6q22.1
• Discovery year
  1986-01-01
• Entrez gene record
  6098
• Pubmed identfication
  • 1611909
• Classification
  • Receptor tyrosine kinases
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000016188
• Locus Specific Databases
  • LRG_997

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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