anti-ATG4C Antibody

• Catalog number
  7907
• Price
  Please ask
• Size
  0.02 mg, 0.1 mg

• Gene info
  Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components (1,2). ATG4C, also known as autophagin-3, is one of four mammalian orthologs of the yeast ATG4 protein; all four are cysteine proteases (3). Recent studies have shown that ATG4C and Beclin-1 are regulated by the microRNA miR-376b; overexpression of miR-376b led to decreased mRNA and protein levels, thereby blocking starvation and TOR inhibition-related autophagy (4).
• Gene names
  ATG4C Antibody: APG4C, AUTL1, AUTL3, APG4-C, APG4C, Cysteine protease ATG4C, AUT-like 3 cysteine endopeptidase
• Antibodie s label
  unlabelled serum
• Purity
  ATG4C antibody is affinity chromatography purified via peptide column.
• Ab raised in
  Rabbit
• Type
  Polyclonal
• Immunoglobulin
  IgG
• Spicific to
  ATG4C antibody is human, mouse and rat reactive. ATG4C is predicted to not cross-react with other ATG4 proteins.
• Antigen
  ATG4C antibody was made against an 18 amino acid peptide near the carboxy terminus of human ATG4C
• Immuno application
  ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
• Antibody advice
  ATG4C antibody can be used for detection of ATG4C by Western blot at 1 - 2 ug/ml. Antibody can also be used for Immunohistochemistry starting at 5 ug/mL. For immunofluorescence start at 20 ug/mL.
• Suspention pH azide
  ATG4C antibody is supplied in PBS containing 0.02% sodium azide.
• Keep at
  ATG4C antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year.
• Works with
  Human, Mouse, Rat
• Omim nr
  30410846
• Ncbi nr
  NP_835739
• KDa
  Predicted: 50 kDa Observed: 57 kDa
• Vial with antibody
  in solution
• Quantity per ml
  1 mg/mL
• NCBI GENE nr
  84938
• GENE symbol
  ATG4C
• Antigene name
  autophagy related 4C, cysteine peptidase
• Source
  homo sapiens
• Protein nr
  Q96DT6
• Picture
• Pdf tech file
• More antibodies
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ATG4C  
• Gene symbol
  ATG4C
• Short name
  anti-ATG4C Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Alternative name
  Antibody toATG4C (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:16040
• Gene
  ATG4C
• Long gene name
  autophagy related 4C cysteine peptidase
• Synonyms gene
  • AUTL1
  • APG4C
• Synonyms gene name
  • AUT (S. cerevisiae)-like 1, cysteine endopeptidase; AUT-like 1, cysteine endopeptidase (S. cerevisiae)
  • APG4 autophagy 4 homolog C (S. cerevisiae)
  • ATG4 autophagy related 4 homolog C (S. cerevisiae)
  • autophagy related 4C, cysteine peptidase
• Synonyms
  • FLJ14867
  • AUTL3
• GenBank acession
  • AK027773
• Locus
  1p31.3
• Discovery year
  2001-07-13
• Entrez gene record
  84938
• Pubmed identfication
  • 12446702
• RefSeq identity
  • NM_032852
• Classification
  • Autophagy related
• VEGA ID
  OTTHUMG00000009142

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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