Fibrinogen Type 1 Antibody
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Catalog number
bs-50576R
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Price
Please ask
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Size
0.1ml
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Long name
Fibrinogen Type 1 Primary Polyclonal Antibody
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Also known as
Fibrinogen Type 1 PAb
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Category
Primary Antibodies
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Conjugation
Unconjugated
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Target Antigen
Fibronectin Type 1
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Specificity
This is a highly specific antibody against Fibronectin Type 1.
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Modification s
None
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Modification site s
Unmodified antibody
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Clonality
Polyclonal antibody
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Clone number
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
Fibrinogen protein purified from Human plasma
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Gene ID number
2243
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Swiss Prot
P02671
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Tested Applications
WB
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Recommended dilutions
WB (1:2,000)
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Cross reactivity
Human
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Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigen
Cleaved by the protease thrombin to yield monomers which, together with fibrinogen beta (FGB) and fibrinogen gamma (FGG), polymerize to form an insoluble fibrin matrix. Fibrin has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the immune response via both innate and T-cell mediated pathways.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym names
Fib2; Fibrinogen alpha chain; FGA
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Properties
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps
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Gene target
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Gene symbol
FCN1, FIBCD1, FGL1
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Short name
Anti-Fibronectin Type 1
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Technique
Antibody, antibodies against human proteins, antibodies for
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Host
Rabbit (Oryctolagus cuniculus)
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Isotype
Immunoglobulin G (IgG)
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Alternative name
Fibrinogen Type 1 Polyclonal Antibody
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Alternative technique
antibodies
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Gene info
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Identity
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Gene
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Long gene name
ficolin 1
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Synonyms gene name
- ficolin (collagen/fibrinogen domain-containing) 1
- ficolin (collagen/fibrinogen domain containing) 1
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Synonyms
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GenBank acession
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Locus
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Discovery year
1996-07-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fibrinogen C domain containing
- Complement system activation components
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VEGA ID
Gene info
Gene info
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Identity
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Gene
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Long gene name
fibrinogen like 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year
1995-05-25
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Fibrinogen C domain containing
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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