FBXL11 Antibody

• Catalog number
  bs-6943R
• Price
  Please ask
• Size
  0.1ml

• Long name
  FBXL11 Primary Polyclonal Antibody
• Also known as
  FBXL11 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  FBXL11
• Specificity
  This is a highly specific antibody against FBXL11.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FBXL11
• Gene ID number
  22992
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  F-box proteins are critical components of the SCF (Skp1-CUL-1-F-box protein) type E3 ubiquitin ligase complex and are involved in substrate recognition and protein recruitment. F-box proteins are members of a large family that regulate the cell cycle, immune response, signaling cascades and developmental programs by targeting proteins, such as cyclins, for degradation by the proteasome after ubiquitination. FBL11, also known as FBXL11 (F-box and leucine-rich repeat protein 11), CXXC8, KDM2A, JHDM1A (JmjC domain-containing histone demethylation protein 1A) or LILINA, is a 1,162 amino acid member of the F-box protein family that contains one F-box domain and localizes to the nucleus. Expressed ubiquitously with highest expression in testis, ovary and brain, FBL11 functions to demethylate the Lys-36 residue of histone H3, thereby modulating the histone code. Additionally, FBL11 is thought to promote the ubiquitination and subsequent degradation of various phosphorylated proteins. Three isoforms of FBL11 exist due to alternative splicing events.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  [Histone-H3]-lysine-36 demethylase 1A; CXXC-type zinc finger protein 8; CXXC8; F box / LRR repeat protein 11; F box and leucine rich repeat protein 11; F box protein FBL7; F-box and leucine-rich repeat protein 11; F-box protein FBL7; F-box protein Lilina; F-box/LRR-repeat protein 11; FBL11; FBL7; FBXL11; JHDM1A; JmjC domain-containing histone demethylation protein 1A; kdm2a; KDM2A_HUMAN; Lysine-specic demethylase 2A.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  FBXL11  
• Gene symbol
  KDM2A
• Short name
  Anti-FBXL11
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  FBXL11 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:13606
• Gene
  KDM2A
• Long gene name
  lysine demethylase 2A
• Synonyms gene
  • FBXL11
• Synonyms gene name
  • F-box and leucine-rich repeat protein 11
  • lysine (K)-specific demethylase 2A
• Synonyms
  • KIAA1004
  • FBL11
  • LILINA
  • DKFZP434M1735
  • FBL7
  • FLJ00115
  • CXXC8
  • JHDM1A
• Synonyms name
  • F-box protein FBL11
  • jumonji C domain-containing histone demethylase 1A
• GenBank acession
  • BC047486
• Locus
  11q13.2
• Discovery year
  2000-09-27
• Entrez gene record
  22992
• Pubmed identfication
  • 10231032
  • 10531037
• RefSeq identity
  • NM_012308
• Classification
  • Zinc fingers CXXC-type
  • PHD finger proteins
  • Lysine demethylases
  • F-box and leucine rich repeat proteins
• VEGA ID
  OTTHUMG00000167103

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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