1,5-Isoquinolinediol

• Catalog number
  2415-10
• Price
  Please ask
• Size
  10 mg

• Alternative_name
  1,5-Dihydroxyisoquinoline, 5-Hydroxy-1(2H)-isoquinolinone, DiQ; NSC 65585
• Description
  1,5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC₅₀ = 0.39 μM). It has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. Also acts as a neuroprotective agent.
• CAS Number
  5154-02-9
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₉H₇NO₂
• Molecular Weight
  161.16
• Cell Permeable
  Yes
• Purity
  ≥98% by TLC
• Solubilities
  DMSO (>35 mg/ml)
• Handling
  Protect from light and air
• Tag Line
  A poly(ADP-ribose) synthetase (PARP1) inhibitor
• Storage Condition
  -20 ̊C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD00006900
• PubChem CID
  1340
• PubChem CID Link
• SMILES
  C1=CC2=C(C=CNC2=O)C(=C1)O
• InChi
  InChI=1S/C9H7NO2/c11-8-3-1-2-7-6(8)4-5-10-9(7)12/h1-5,11H,(H,10,12)
• InChi Key
  LFUJIPVWTMGYDG-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  5-Isoquinolinediol  
• Short name
  1 5-Isoquinolinediol
• Alternative name
  1,5-Isoquinolinediol

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