1,5-Isoquinolinediol
-
Catalog number2415-50
-
PricePlease ask
-
Size50 mg
-
-
Alternative_name1,5-Dihydroxyisoquinoline, 5-Hydroxy-1(2H)-isoquinolinone, DiQ; NSC 65585
-
Description1,5-Isoquinolinediol is an inhibitor of poly(ADP-ribose) synthetase (PARP1; IC₅₀ = 0.39 μM). It has been used to study the role of PARP1 in both DNA repair and oxidant stress-induced cell death. Also acts as a neuroprotective agent.
-
CAS Number5154-02-9
-
Structure AvailableYes
-
Salt FormNo
-
Molecular FormulaC₉H₇NO₂
-
Molecular Weight161.16
-
Cell PermeableYes
-
Purity≥98% by TLC
-
SolubilitiesDMSO (>35 mg/ml)
-
HandlingProtect from light and air
-
Tag LineA poly(ADP-ribose) synthetase (PARP1) inhibitor
-
Storage Condition-20 ̊C
-
Shipping Conditiongel pack
-
Shelf Life36 months
-
MDL NumberMFCD00006900
-
PubChem CID1340
-
SMILESC1=CC2=C(C=CNC2=O)C(=C1)O
-
InChiInChI=1S/C9H7NO2/c11-8-3-1-2-7-6(8)4-5-10-9(7)12/h1-5,11H,(H,10,12)
-
InChi KeyLFUJIPVWTMGYDG-UHFFFAOYSA-N
-
MSDS AvailableYes
-
Gene target
-
Short name1 5-Isoquinolinediol
-
Alternative name1,5-Isoquinolinediol
-