Thioredoxin isoform 1 (Trx), Active, Human Recombinant

• Catalog number
  P1039-100
• Price
  Please ask
• Size
  100 ug

• Synonyms
  TXN, TRX, TRX1, Thioredoxin 1
• Alternative_names
  TXN, TRX, TRX1, Thioredoxin 1
• Description
  A protein involved in redox signaling
• Recombinant
  Yes
• Source
  E. coli
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Activity Specifications test method
  Measured by its ability to reduce FITC-labeled oxidized glutathione (FITC-GSSG-FITC) to FITC-labeled reduced glutathione (FITC-GSH).
• Biological activity
  This enzyme has activity ≥20 mU/mg based on its ability to reduce FITC-labeled oxidized glutathione (FITC-GSSG-FITC) to FITC-labeled reduced glutathione (FITC-GSH).
• Results
  Enzymatic activity is ≥20 U/mg
• Molecular Weight
  14.5 kDa (130 aa)
• Storage Temp
  4°C
• Shipping
  Gel Pack
• Shelf Life
  12 months
• Appearance
  Lyophilized
• Reconstitution Instructions
  Reconstitute in deionized water.
• Background Information
  Thioredoxin (Trx) is a disulfide reductase that reduces disulfide bonds into thiol groups through a thiol-disulfide exchange with its target proteins to regulate oxidative stress and redox signaling. Trx activity is dependent on NADPH and Thioredoxin Reductase’s (TrxR) ability to reduce it at Cysteine 32 and Cysteine 35.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  Thioredoxin   isoform   Trx   Active  
• Short name
  Thioredoxin isoform 1 (Trx), Active, Recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Human, Humans
• Alternative name
  Thioredoxin isoform 1 (Trx), functionnal, H. sapiens Rec.
• Alternative technique
  rec

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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