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BAX Activator BAM7

BAX Activator BAM7 is available 4 times from Biovision labs

2451-5 | BAX Activator, BAM7 size: 2X5 mg | 387.46 USD

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2451-25 | BAX Activator, BAM7 size: 25 mg | 598.29 USD

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2451-25 | BAX Activator, BAM7 for cell activation size: 25 mg | 521.94 USD

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2451-5 | BAX Activator, BAM7 for cell activation size: 5 mg | 174.36 USD

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Description A potent and selective BAX activator (EC₅₀ = 3.3 μM). BAM7 directly binds at the BH3-binding site; selective for BAX over other antiapoptotic and proapoptotic proteins. BAM7 triggers in vitro BAX oligomerization, BAX-mediated pore formation and BAX-dependent cell death. BAM7 selectively induces BAX-mediated apoptosis by triggering the hallmark features of intracellular BAX activation. BAM7 only kills the cell line that contains BAX, eliciting the biochemical and morphologic features of BAX-mediated apoptosis.
Peptide sequence N/A
CAS number 331244-89-4
Molecular weight 405.47
Category Biochemicals
Other name 3-Methyl-1-(4-phenyl-2-thiazolyl)-1​H-pyrazole-4,5-dione 4-[2-(2-Ethoxyphenyl)hydrazone]; BAM7
Molecular formula C₂₁H₁₉N₅O₂S
Physical appearance Brown solid
Supplied with N/A
Is this a salt? No
Is it cell-permeable? Yes
Purification ≥98% by HPLC
Storage condition -20°C
Shipping condition gel pack
Maximum time for storage 24 months
Storage instructions Protect from air and light
Alternate Name/Synonyms 3-Methyl-1-(4-phenyl-2-thiazolyl)-1​H-pyrazole-4,5-dione 4-[2-(2-Ethoxyphenyl)hydrazone]; BAM7
Appearance Brown solid
Formulation N/A
CAS Number 331244-89-4
Molecular Formula C₂₁H₁₉N₅O₂S
Molecular Weight 405.47
Purity ≥98% by HPLC
Handling Protect from air and light
Tagline A potent and selective BAX activator
Storage Temp. -20°C
Shipping Conditions gel pack
Shelf Life 24 months
MDL Number N/A
PubChem CID 5754137
Alternative to gene target BCL2-associated X protein, BCL2L4, BAX and IDBG-61459 and ENSG00000087088 and 581, BH3 domain binding, nuclei, Bax and IDBG-183241 and ENSMUSG00000003873 and 12028, BAX and IDBG-640344 and ENSBTAG00000013340 and 100850136,280730
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BAX Activator BAM7 - Biovision - Gentaur.com
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