Description
The receptors are ligand binding factors of type 1, 2 or 3 and protein-molecules that receive chemical-signals from outside a cell. When such chemical-signals couple or bind to a receptor, they cause some form of cellular/tissue-response, e.g. a change in the electrical-activity of a cell. In this sense, am olfactory receptor is a protein-molecule that recognizes and responds to endogenous-chemical signals, chemokinesor cytokines e.g. an acetylcholine-receptor recognizes and responds to its endogenous-ligand, acetylcholine. However, sometimes in pharmacology, the term is also used to include other proteins that are drug-targets, such as enzymes, transporters and ion-channels.
Identity 12680
Gene VEGFA
Long gene name vascular endothelial growth factor A
Synonyms gene name- vascular endothelial growth factor
Locus 6p21.1
Discovery year 1994-01-10
Entrez gene record 7422
Havana BLAST/BLAT OTTHUMG00000014745
Locus Specific Databases- ALSOD, the Amyotrophic Lateral Sclerosis Online Genetic Database
Identity 3767
Gene FLT4
Long gene name fms related receptor tyrosine kinase 4
Synonyms gene name- fms-related tyrosine kinase 4
- fms related tyrosine kinase 4
Synonyms name- vascular endothelial growth factor receptor 3
- VEGF receptor-3
- Feline McDonough Sarcoma (FMS)-like tyrosine kinase 4
- primary congenital lymphedema
Locus 5q35.3
Discovery year 1991-10-25
Entrez gene record 2324
Classification- Receptor tyrosine kinases
- I-set domain containing
Havana BLAST/BLAT OTTHUMG00000130931
