Crenolanib Trifluoroacetic Acid Salt

Chemical available in other sizes

Please inquire size and price
Stock availability

Pending QC
Cas number

1797008-57-1
Chemical s molecular weight

557.56
Chemical s main applications

Crenolanib (CP-868569) is a tyrosine kinase inhibitor that acts by specifically inhibiting the receptor tyrosine kinases PDGFRα and PDGFRβ. Crenolanib (CP-868569) inhibits the activity of PDGFRα D842V kinase and prevented the phosphorylation of wild type PDGFRα. Crenolanib (CP-868569) possesses potential antineoplastic activity. Crenolanib is believed to suppress PDGFR-related signal transduction pathways leading to the inhibition of tumor angiogenesis and tumor cell proliferation.
Chemical s category

Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Tyrosine Kinase Inhibitors,
Other name

1-[2-[5-[(3-Methyl-3-oxetanyl)methoxy]-1H-benzimidazol-1-yl]-8-quinolinyl]-4-piperidinamine Trifluoroacetic Acid Salt; ARO 002 Trifluoroacetic Acid Salt; CP 868596 Trifluoroacetic Acid Salt; [1-[2-[5-(3-Methyloxetan-3-ylmethoxy)benzimidazol-1-yl]quinolin-8-yl]piperidin-4-yl]amine Trifluoroacetic Acid Salt;
Chemical s formula

C28H30F3N5O4
Physical properties

White to Off-White Solid
Melting temperature

217-220°C
Boiling temperature

No Data Available
Chemical s soluble in

DMSO, Methanol
Stability conditions

No Data Available
Storage

Refrigerator
Chemical s specifications