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Gene info
KLRA2 Antibody: KLRA2 (also known as Ly49B) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA2 is thought to be an inhibitory receptor and associates with the protein tyrosine phosphatases SHP1, SHP2, and SHIP in transfected cells. This antibody is predicted to not cross-react with other LY49 receptors.
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Gene names
KLRA2 Antibody: Ly49b, Klra30, Ly49-b, Ly49b, Killer cell lectin-like receptor 2, Lymphocyte antigen 49b, Ly-49b
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Antibodie s label
unlabelled serum
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Purity
KLRA2 Antibody is affinity chromatography purified via peptide column.
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Ab raised in
Rabbit
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Type
Polyclonal
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Immunoglobulin
IgG
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Antigen
KLRA2 antibody was made against a 14 amino acid synthetic peptide near the carboxy terminus of mouse KLRA2.
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Immuno application
ELISA, Western Blot, immuno-histo-chemistry, immuno fluorescence
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Antibody advice
KLRA2 antibody can be used for detection of KLRA2 by Western blot at 0.5 - 1 ug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 ug/mL. For immunofluorescence start at 20 ug/mL.
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Suspention pH azide
KLRA2 Antibody is supplied in PBS containing 0.02% sodium azide.
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Keep at
KLRA2 antibody can be stored at 4 grades C for three months and -20 grades C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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Works with
Mouse, Rat
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Omim nr
2497636
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Ncbi nr
Q60660
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Vial with antibody
in solution
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Quantity per ml
1 mg/mL
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NCBI GENE nr
16633
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GENE symbol
Klra2
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Antigene name
killer cell lectin-like receptor, subfamily A, member 2
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Source
Mus musculus
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Protein nr
Q60660
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Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
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Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translation
anticorps