Phytosphingosine, Kinase Activator

  • Catalog number
    SIH-524-25MG
  • Price
    Please ask
  • Size
    25 mg
  • Stock availabilitIn Stock
    In Stock
  • CAS number
    554-62-1
  • Description
    Kinase Activator
  • Molecular weight
    317.5 g/mol
  • Primary research fields
    Cancer, Oxidative Stress
  • Other name
    (2S,3R,4R)-Octadecane-1,2,3,4-tetraol
  • Product category
    Small Molecules
  • Product type
    Activator
  • Chemical formula
    C18H39NO3
  • Origin
    Isolated from Saccharomyces cerevisiae
  • Purity pourcentage
    >98% (TLC); NMR (Conforms)
  • Soluble in
    Soluble to 2 mg/ml in ethanol
  • Physical appearance
    White powder
  • Storage recommendations
    -20ÂșC
  • Shipping recommendations
    Shipped Ambient
  • Safety information
    Classification: Not WHMIS controlled. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
  • PubChem number
    122121
  • Scientific context
    Phytosphingosine is a naturally occurring component found in yeast, plants and animals. In yeast, it is involved in mediating the heat stress response. Phytosphingosine has been found to be pro-apoptotic in certain cancer cell lines. It is thought to activate the p38 MAPK pathway, followed by release of cytochrome c and activation of caspase 3, ultimately leading to programed cell death.
  • Bibliography
    1. Fischer C., et al. (2013) Skin Pharmacol Physiol. 26(1): 36-44.
  • Release date
    1-Oct-2014
  • PubMed number
    Refer to PubMed
  • Tested applications
    To be tested
  • Tested reactivity
    To be tested
  • Representative figure legend
    Chemical structure of Phytosphingosine (SIH-524), a Antibacterial. CAS #: 554-62-1. Molecular Formula: C18H39NO3. Molecular Weight: 317.5 g/mol. Chemical structure of Phytosphingosine, a Antibacterial (SIH-524). CAS # 554-62-1. Molecular Formula: C18H39NO3.
  • Warning information
    Non-hazardous
  • Country of production
    Canada
  • Total weight kg
    0.25
  • Net weight g
    0.025
  • Gene target
  • Short name
    Phytosphingosine, Kinase Activator
  • Alternative name
    Phytosphingosine, phosphorylation catalyst Activator
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