Phytosphingosine, Kinase Activator
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Catalog number
SIH-524-25MG
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Price
Please ask
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Size
25 mg
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Stock availabilitIn Stock
In Stock
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CAS number
554-62-1
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Description
Kinase Activator
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Molecular weight
317.5 g/mol
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Primary research fields
Cancer, Oxidative Stress
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Other name
(2S,3R,4R)-Octadecane-1,2,3,4-tetraol
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Product category
Small Molecules
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Product type
Activator
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Chemical formula
C18H39NO3
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Origin
Isolated from Saccharomyces cerevisiae
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Purity pourcentage
>98% (TLC); NMR (Conforms)
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Soluble in
Soluble to 2 mg/ml in ethanol
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Physical appearance
White powder
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Storage recommendations
-20ÂșC
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Shipping recommendations
Shipped Ambient
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Safety information
Classification: Not WHMIS controlled. Safety Phrases: S22 - Do not breathe dust. S24/25 - Avoid contact with skin and eyes. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
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PubChem number
122121
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Scientific context
Phytosphingosine is a naturally occurring component found in yeast, plants and animals. In yeast, it is involved in mediating the heat stress response. Phytosphingosine has been found to be pro-apoptotic in certain cancer cell lines. It is thought to activate the p38 MAPK pathway, followed by release of cytochrome c and activation of caspase 3, ultimately leading to programed cell death.
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Bibliography
1. Fischer C., et al. (2013) Skin Pharmacol Physiol. 26(1): 36-44.
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Release date
1-Oct-2014
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PubMed number
Refer to PubMed
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Tested applications
To be tested
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Tested reactivity
To be tested
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Representative figure legend
Chemical structure of Phytosphingosine (SIH-524), a Antibacterial. CAS #: 554-62-1. Molecular Formula: C18H39NO3. Molecular Weight: 317.5 g/mol. Chemical structure of Phytosphingosine, a Antibacterial (SIH-524). CAS # 554-62-1. Molecular Formula: C18H39NO3.
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Warning information
Non-hazardous
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Country of production
Canada
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Total weight kg
0.25
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Net weight g
0.025
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Gene target
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Short name
Phytosphingosine, Kinase Activator
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Alternative name
Phytosphingosine, phosphorylation catalyst Activator
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