anti- AKTIP antibody

• Catalog number
  FNab00274
• Price
  Please ask
• Size
  2X100μg

• Form
  liquid
• Purification
  Immunogen affinity purified
• Purity
  ≥95% as determined by SDS-PAGE
• Storage
  PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
• Background
  The mouse homolog of this gene produces fused toes and thymic hyperplasia in heterozygous mutant animals while homozygous mutants die in early development. This gene may play a role in apoptosis as these morphological abnormalities are caused by altered patterns of programmed cell death. The protein encoded by this gene is similar to the ubiquitin ligase domain of other ubiquitin-conjugating enzymes but lacks the conserved cysteine residue that enables those enzymes to conjugate ubiquitin to the target protein. This protein interacts directly with serine/threonine kinase protein kinase B (PKB)/Akt and modulates PKB activity by enhancing the phosphorylation of PKB's regulatory sites. Alternative splicing results in two transcript variants encoding the same protein.
• Immunogen
  AKT interacting protein
• Synonyms
  AKT interacting protein, AKTIP, FT1, FTS, Fused toes protein homolog
• Calculated MW
  36 kDa
• Uniprot ID
  Q9H8T0
• Specificity
  Human, Mouse, Rat
• Tested Application
  ELISA, WB, IHC
• Recommended dilution
  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
• Image4
  mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with FNab00274( AKTIP Antibody) at dilution of 1:1000
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Properties
  If you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  AKTIP  
• Gene symbol
  AKTIP
• Short name
  anti- AKTIP antibody
• Technique
  Antibody, anti, antibody to, antibodies against human proteins, antibodies for
• Host
  Rabbit
• Isotype
  IgG
• Alternative name
  antibody to- AKT interacting protein (antibody to-)
• Alternative technique
  antibodies
• Alternative to gene target
  AKT interacting protein, AKTIP and IDBG-31049 and ENSG00000166971 and 64400, acid-amino acid ligase activity, Plasma membranes, Aktip and IDBG-179747 and ENSMUSG00000031667 and 14339, AKTIP and IDBG-631788 and ENSBTAG00000016250 and 540462

Gene info

• Identity
  HGNC:16710
• Gene
  AKTIP
• Long gene name
  AKT interacting protein
• Synonyms gene
  • FTS
• Synonyms gene name
  • fused toes homolog (mouse)
• Synonyms
  • FLJ13258
• Synonyms name
  • fused toes homolog
• GenBank acession
  • AK023320
• Locus
  16q12.2
• Discovery year
  2001-10-02
• Entrez gene record
  64400
• Pubmed identfication
  • 7818539
  • 8626685
• RefSeq identity
  • NM_022476
• Classification
  • FHF complex
  • Ubiquitin conjugating enzymes E2
• VEGA ID
  OTTHUMG00000133199

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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