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Anti Rat PlGF

Anti Rat PlGF is available 3 times from Reliatech antibodies labs

104-PA04 | Anti-Rat PlGF size: 200ug | 310.84 USD

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104-PA04AG | Anti-Rat PlGF size: 50ug | 221.37 USD

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104-PA04S | Anti-Rat PlGF size: 100ug | 206.46 USD

Catalog number 104-PA04S
Price206.46 USD
Size 100ug
1. Gene info
Identity8894
GenePGFL
Long gene name placental growth factor
Synonyms gene name
  • placental growth factor-like
  • placental growth factor, vascular endothelial growth factor-related protein
GenBank acession
Locus14q24.3
Discovery year 1994-01-14
Entrez gene record5228
Pubmed identfication
RefSeq identity
Classification
  • VEGF family
Havana BLAST/BLATOTTHUMG00000171496
MeSH Data
Concept
Scope note:Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
Additional information
PubMedEndothelial cell-released H2O2 acts as a positive regulator of placenta growth factor gene and protein expression in vascular smooth muscle cells.
This is the first demonstration that sustained intraocular PGF production induces vascular and retinal changes similar to those observed in the early stages of diabetic retinopathy.
augmentation of brain Placental growth factor is associated with development of epilepsy.
PLGF expression in the lung tissue in rats with paraquat-induced pulmonary fibrosis is upregulated.
The results of this study disclosed a constant down-regulation of the vascular endothelial growth factor (VEGF), and transient decreases of angiopoietin-1 (Ang-1), platelet-derived growth factor-BB (PDGF-BB), as well as placental growth factor (PlGF).
VEGFB and PlGF can either inhibit or potentiate the actions of VEGFA, depending on their relative concentrations, which change in the hypoxic lung.
Intramyocardial injections of autologous myoblasts overexpressing placental growth factor improved cardiac function, attenuated adverse cardiac remodeling, induced angiogenesis, and probably enhanced survival of grafted myoblasts.
Our findings suggest that VEGF and PLGF enhance blood brain barrier permeability through different VEGFR pathways and that circulating sFlt1 prevents VEGF- and PLGF-induced BBB permeability during pregnancy.
placental gene expression is modulated by gestational conditions that might disrupt the fetal growth
PlGF had a positive feedback regulation with 15-lipoxygenase expression and 15-hydroxyeicosatetraenoic acid generation.
Gene ontology - Cellular componentextracellular space
membrane
Product images
    #.png#Rat#.png
Synonyms Pgf; Plgf; placental growth factor
Storage and handling Lyophilized antibodies can be shipped at ambient temperature and stored for short terms at +4 degrees Celsius and at -20 for long term storage. Reconstituted lyophilised and antibodies in liquid form can be shipped and stored for short terms at +4 degrees Celsius. Generally, it is recomended for long term storage (up to one year) 25-50% glycerol or ethylene glycol to be added and the vial must be stored at -20°C.
Description This is a highly purified antibody with strong binding affinity towards the antigen that it has been risen against.Properly used, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in.
Species Reactivity Rat (Rattus norvegicus)
Advisory In order to retain the quality and the affinity of the antibodies unchanged, please, avoid cycles of freezing and thawing. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
Uniprot Q63434
Gene Name PlGF
Additional description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
About Rats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
Latin name Rattus norvegicus
Gene targetPlGF
Short name Anti- PlGF
Technique anti
Host Rat
Species Rat
Alternative name antibody to-Rat PlGF
Alternative technique antibodies
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